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Table 1 Clinicopathologic features of patients subjected to different chemotherapy regimens

From: Impact of timing of adjuvant chemotherapy on survival in stage III colon cancer: a population-based study

  No-chemo 5FU/Capecitabine FOLFOX/CapeOX
Gender
 Male 3124 3591 799
 Female 5645 4467 865
Age at diagnosis, years
 66–70 554 1826 584
 71–75 1002 2422 514
 76–80 1784 2180 419
  > 80 5429 1630 147
Race
 White 7369 6909 1407
 Black 841 592 132
 Asian 244 260 52
 Other 315 297 73
Marital status
 Single+Separated 823 551 125
 Married 3105 4620 1044
 Divorced+Widowed 4535 2654 443
 Other 306 233 52
Residence location
 Big Metro 4802 4219 878
 Metro or Urban 2963 2853 588
 Less Urban or Rural 1002 986 198
Median household income
 1st quartile 2203 1803 371
 2nd quartile 2102 1976 375
 3rd quartile 2062 1949 393
 4th quartile 2035 2029 443
 Unknown 367 301 82
Level of education
 1st quartile 2064 2003 401
 2nd quartile 2029 2015 373
 3rd quartile 2136 1920 400
 4th quartile 2173 1819 408
 Unknown 367 301 82
Year of diagnosis
 1992–1996 1837 1902 0
 1997–2000 1678 1887 0
 2001–2004 2739 3169 240
 2005–2008 2515 1100 1424
Primary tumor site
 right-sided colon 5867 5111 1068
 left-sided colon 2730 2809 572
 unknown 172 138 24
Histologic grade
 Well 432 422 99
 Moderate 5360 5169 1046
 Poor+Undifferentiated 2756 2251 486
 Unknown 221 216 33
Histologic type
 Adenocarcinoma 7402 6811 1425
 Mucinous carcinoma 1216 1140 212
 Signet-ring cell carcinoma 151 107 27
pT category
 pT1 173 302 69
 pT2 571 721 150
 pT3 6185 5805 1223
 pT4a 1040 861 150
 pT4b 800 369 72
pN category
 pN1a 3315 2898 500
 pN1b 2889 2750 554
 pN2a 1550 1518 357
 pN2b 1015 892 253
pTNM stage
 pTNM IIIa 673 920 190
 pTNM IIIb 6239 5814 1132
 pTNM IIIc 1857 1324 342
Preoperative intestinal obstruction
 No 6406 6648 1367
 Yes 2363 1410 297
Preoperative intestinal perforation
 No 8576 7998 1648
 Yes 193 60 16
HCC risk score
 1st quartile 2557 1811 289
 2nd quartile 1685 2427 539
 3rd quartile 1972 2195 492
 4th quartile 2555 1625 344
Number of examined lymph node
  ≥ 12 4674 4274 1213
  < 12 4095 3784 451
Postoperative radiotherapy
 No 8692 7765 1639
 Yes 77 293 25
Timing to AC
  ≤ 4 weeks 0 660 86
 5–8 weeks 0 5118 1047
 9–12 weeks 0 1502 381
 13–16 weeks 0 369 97
  ≥ 17 weeks 0 409 53
 No-chemo 8769 0 0
  1. Abbreviation: AC Adjuvant chemotherapy, HCC Hierarchical Condition Categories; No-chemo, without adjuvant chemotherapy, 5-FU 5-fluorouracil, FOLFOX/CapeOX 5-FU/capecitabine plus oxaliplatin