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Table 1 Clinicopathologic features of patients subjected to different chemotherapy regimens

From: Impact of timing of adjuvant chemotherapy on survival in stage III colon cancer: a population-based study

 

No-chemo

5FU/Capecitabine

FOLFOX/CapeOX

Gender

 Male

3124

3591

799

 Female

5645

4467

865

Age at diagnosis, years

 66–70

554

1826

584

 71–75

1002

2422

514

 76–80

1784

2180

419

  > 80

5429

1630

147

Race

 White

7369

6909

1407

 Black

841

592

132

 Asian

244

260

52

 Other

315

297

73

Marital status

 Single+Separated

823

551

125

 Married

3105

4620

1044

 Divorced+Widowed

4535

2654

443

 Other

306

233

52

Residence location

 Big Metro

4802

4219

878

 Metro or Urban

2963

2853

588

 Less Urban or Rural

1002

986

198

Median household income

 1st quartile

2203

1803

371

 2nd quartile

2102

1976

375

 3rd quartile

2062

1949

393

 4th quartile

2035

2029

443

 Unknown

367

301

82

Level of education

 1st quartile

2064

2003

401

 2nd quartile

2029

2015

373

 3rd quartile

2136

1920

400

 4th quartile

2173

1819

408

 Unknown

367

301

82

Year of diagnosis

 1992–1996

1837

1902

0

 1997–2000

1678

1887

0

 2001–2004

2739

3169

240

 2005–2008

2515

1100

1424

Primary tumor site

 right-sided colon

5867

5111

1068

 left-sided colon

2730

2809

572

 unknown

172

138

24

Histologic grade

 Well

432

422

99

 Moderate

5360

5169

1046

 Poor+Undifferentiated

2756

2251

486

 Unknown

221

216

33

Histologic type

 Adenocarcinoma

7402

6811

1425

 Mucinous carcinoma

1216

1140

212

 Signet-ring cell carcinoma

151

107

27

pT category

 pT1

173

302

69

 pT2

571

721

150

 pT3

6185

5805

1223

 pT4a

1040

861

150

 pT4b

800

369

72

pN category

 pN1a

3315

2898

500

 pN1b

2889

2750

554

 pN2a

1550

1518

357

 pN2b

1015

892

253

pTNM stage

 pTNM IIIa

673

920

190

 pTNM IIIb

6239

5814

1132

 pTNM IIIc

1857

1324

342

Preoperative intestinal obstruction

 No

6406

6648

1367

 Yes

2363

1410

297

Preoperative intestinal perforation

 No

8576

7998

1648

 Yes

193

60

16

HCC risk score

 1st quartile

2557

1811

289

 2nd quartile

1685

2427

539

 3rd quartile

1972

2195

492

 4th quartile

2555

1625

344

Number of examined lymph node

  ≥ 12

4674

4274

1213

  < 12

4095

3784

451

Postoperative radiotherapy

 No

8692

7765

1639

 Yes

77

293

25

Timing to AC

  ≤ 4 weeks

0

660

86

 5–8 weeks

0

5118

1047

 9–12 weeks

0

1502

381

 13–16 weeks

0

369

97

  ≥ 17 weeks

0

409

53

 No-chemo

8769

0

0

  1. Abbreviation: AC Adjuvant chemotherapy, HCC Hierarchical Condition Categories; No-chemo, without adjuvant chemotherapy, 5-FU 5-fluorouracil, FOLFOX/CapeOX 5-FU/capecitabine plus oxaliplatin