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Table 4 Adjusted odds ratio of lung cancer by smoking status according to BMI categories

From: Body mass index and lung cancer risk: a pooled analysis based on nested case-control studies from four cohort studies

BMI (kg/m2) a   Men and Women   Men   Women
  Cases Controls Adjusted OR (95% CI) b Cases Controls Adjusted OR (95% CI) c Cases Controls Adjusted OR (95% CI) c
Never Smokers
 Underweight 33 161 0.83 (0.53–1.28) 15 97 0.88 (0.49–1.60) 18 64 0.84 (0.42–1.68)
 Normal weight 334 1794 Reference 169 1159 Reference 165 635 Reference
 Overweight 117 916 0.77 (0.59–0.99) 46 540 0.74 (0.51–1.06) 71 376 0.75 (0.51–1.11)
 Obese 29 233 0.71 (0.44–1.14) 5 110 0.55 (0.22–1.40) 24 123 0.73 (0.40–1.36)
 Missing 58 40 19 15 39 25
Former Smokers
 Underweight 10 58 0.27 (0.12–0.61) 8 51 0.26 (0.11–0.61) 2 7 0.27 (0.02–3.69)
 Normal weight 262 609 Reference 203 477 Reference 59 132 Reference
 Overweight 272 729 0.70 (0.53–0.93) 224 599 0.66 (0.48–0.91) 55 130 0.77 (0.36–1.65)
 Obese 105 297 0.55 (0.37–0.80) 83 230 0.51 (0.33–0.79) 22 67 0.67 (0.27–1.67)
 Missing 38 42   26 15 27
Current Smokers
 Underweight 207 189 1.24 (0.98–1.58) 173 162 1.26 (0.98–1.63) 34 27 0.82 (0.38–1.76)
 Normal weight 1549 1860 Reference 1234 1511 Reference 315 349 Reference
 Overweight 710 1085 0.79 (0.68–0.92) 537 853 0.75 (0.63–0.88) 173 232 0.87 (0.62–1.23)
 Obese 237 400 0.75 (0.60–0.93) 167 286 0.72 (0.55–0.92) 70 114 0.73 (0.46–1.15)
 Missing 189 22 127 6 62 16
  1. aUnderweight (BMI < 18.5), normal weight (18.5 ≤ BMI < 25), overweight (25 ≤ BMI < 30) and obese (BMI ≥ 30)
  2. bAdjusted for age, gender, study center, time elapsed, pack-years of smoking (except for never smokers) and education level
  3. cAdjusted for age, study center, time elapsed, pack-years of smoking (except for never smokers) and education level
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