Table 3 Prognostic factors associated with OS

Age (y) (≤ 55, > 55)

0.96(0.81–1.22)

Gender (male/female)

1.25(0.89–1.42)

HBsAg (positive/ negative)

0.97(0.78–1.22)

ALB, g/L (≤ 35, > 35)

0.71(0.59–0.85)

TBIL, μmol/L (≤ 28, > 28)

1.65(1.33–2.04)

1.64(1.17–2.29)

0.004

ALT, IU/L (≤ 40 > 40)

1.34(1.13–1.59)

AST, IU/L (≤ 35 > 35)

2.01(1.64–2.47)

PT, sec (≤ 12/ > 12)

1.13(0.95–1.34)

AFP, ng/mL (≤ 400/ > 400)

1.58(1.34–1.87)

Child-pugh grade (A/ B)

1.34(1.09–1.66)

MELD score (≤ 10/ >  10)

1.45(1.09–1.91)

Largest tumor size (cm) (≤ 10/ > 10)

1.75(1.40–2.19)

Tumor number (single/multiple)

1.01(0.83–1.23)

Vascular invasion (present/ absent)

2.02(1.61–2.54)

BCLC (B / C stage)

2.21(1.76–2.77)

1.65(1.24–2.19)

0.001

dNLR (≤ 1.7, > 1.7)

2.17(1.79–2.61)

PNI (≤ 46, > 46)

0.66(0.56–0.78)

 1

–

 2

1.94(1.58–2.37)

2.39(1.69–3.38)

< 0.001

 > 2

1.52(1.21–1.91)

1.39(0.96–2.03)

0.078

 0

–

 1

1.62(1.25–2.09)

1.71(1.08–2.68)

0.022

 2

2.75(2.14–3.53)

3.25(1.74–6.02)

< 0.001