Variables | Univariate | Multivariate | ||
---|---|---|---|---|
HR(95%CI) | P value | HR(95%CI) | P value | |
Age (y) (≤ 55, > 55) | 0.96(0.81–1.22) | 0.413 | ||
Gender (male/female) | 1.25(0.89–1.42) | 0.319 | ||
HBsAg (positive/ negative) | 0.97(0.78–1.22) | 0.8 | ||
ALB, g/L (≤ 35, > 35) | 0.71(0.59–0.85) | < 0.001 | ||
TBIL, μmol/L (≤ 28, > 28) | 1.65(1.33–2.04) | < 0.001 | 1.64(1.17–2.29) | 0.004 |
ALT, IU/L (≤ 40 > 40) | 1.34(1.13–1.59) | 0.001 | ||
AST, IU/L (≤ 35 > 35) | 2.01(1.64–2.47) | < 0.001 | ||
PT, sec (≤ 12/ > 12) | 1.13(0.95–1.34) | 0.173 | ||
AFP, ng/mL (≤ 400/ > 400) | 1.58(1.34–1.87) | < 0.001 | ||
Child-pugh grade (A/ B) | 1.34(1.09–1.66) | 0.006 | ||
MELD score (≤ 10/ > 10) | 1.45(1.09–1.91) | 0.008 | ||
Largest tumor size (cm) (≤ 10/ > 10) | 1.75(1.40–2.19) | < 0.001 | ||
Tumor number (single/multiple) | 1.01(0.83–1.23) | 0.992 | ||
Vascular invasion (present/ absent) | 2.02(1.61–2.54) | < 0.001 | ||
BCLC (B / C stage) | 2.21(1.76–2.77) | < 0.001 | 1.65(1.24–2.19) | 0.001 |
dNLR (≤ 1.7, > 1.7) | 2.17(1.79–2.61) | < 0.001 | ||
PNI (≤ 46, > 46) | 0.66(0.56–0.78) | < 0.001 | ||
TACE treatments (1/ 2/ > 1) | ||||
1 | – | |||
2 | 1.94(1.58–2.37) | < 0.001 | 2.39(1.69–3.38) | < 0.001 |
> 2 | 1.52(1.21–1.91) | < 0.001 | 1.39(0.96–2.03) | 0.078 |
dNLR-PNI | ||||
0 | – | |||
1 | 1.62(1.25–2.09) | < 0.001 | 1.71(1.08–2.68) | 0.022 |
2 | 2.75(2.14–3.53) | < 0.001 | 3.25(1.74–6.02) | < 0.001 |