Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis

Table 5 Comparison of AUC of the varied MRI parameter combinations

Values	AUC	Sensitivity (%)	Specificity (%)	LOOCV Accuracy (%)	LOOCV AUC
rCBF + ADC	0.893	83.1	83.2	81.8	0.871
Location + Necrosis	0.670	62.3	62.3	53.2	0.597
rCBF + Location + Necrosis	0.852	77.9	77.6	72.7	0.821
ADC + Location + Necrosis	0.891	80.5	80.2	79.2	0.845
ALL	0.914	85.7	85.2	80.5	0.877

Note: ADC = apparent diffusion coefficient, rCBF = relative cerebral blood flow, AUC = area under ROC curve, LOOCV = leave-one-out cross-validation, ALL = ADC + rCBF + Location + Necrosis

ISSN: 1471-2407