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Table 5 Comparison of AUC of the varied MRI parameter combinations

From: Structural and advanced imaging in predicting MGMT promoter methylation of primary glioblastoma: a region of interest based analysis

Values AUC Sensitivity (%) Specificity (%) LOOCV
Accuracy
(%)
LOOCV
AUC
rCBF + ADC 0.893 83.1 83.2 81.8 0.871
Location + Necrosis 0.670 62.3 62.3 53.2 0.597
rCBF + Location + Necrosis 0.852 77.9 77.6 72.7 0.821
ADC + Location + Necrosis 0.891 80.5 80.2 79.2 0.845
ALL 0.914 85.7 85.2 80.5 0.877
  1. Note: ADC = apparent diffusion coefficient, rCBF = relative cerebral blood flow, AUC = area under ROC curve, LOOCV = leave-one-out cross-validation, ALL = ADC + rCBF + Location + Necrosis