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Table 3 Ability of mesothelin to predict progression- subgroup analysis

From: A prospective study to investigate the role of serial serum mesothelin in monitoring mesothelioma

  Baseline Mesothelin> = 2 Baseline Mesothelin< 2 Non-Epithelioid
n 19 24 9
Progression on CT (Y/N) 13/6 11/13 5/4
Sensitivity 100 (75.3–100) 90.9 (58.7–99.7) 80.0 (28.4–99.5)
Specificity 83.3 (35.9–99.6) 69.2 (38.5–90.9) 75.0 (19.4–99.4)
PPV 92.7 (68.4–98.7) 71.4 (51.9–85.2) 80.0 (40.9–95.9)
NPV 100 90.0 (57.3–98.4) 75.0 (32.2–94.9)