|  |  |  | 95% confidence interval |  | 95% confidence interval |  | ||
---|---|---|---|---|---|---|---|---|---|
Variable | CRP (mg/dL) | N | Estimated mean methylation (%) | Lower | Upper | βc | Lower | Upper | P value for trend |
Crude model | 0.002–0.011 | 101 | 69.7 | 69.0 | 70.3 |  |  |  |  |
 | 0.012–0.023 | 89 | 70.2 | 69.5 | 70.9 |  |  |  |  |
 | 0.024–0.048 | 93 | 70.7 | 70.0 | 71.3 |  |  |  |  |
 | 0.049–0.491 | 93 | 70.4 | 69.8 | 71.1 |  |  |  |  |
 |  |  |  |  |  | 0.28 | −0.02 | 0.58 | 0.071 |
 | Log-transformed CRP |  |  |  |  | 0.25 | −0.07 | 0.56 | 0.123 |
Adjusted model 1a | 0.002–0.011 | 100 | 70.1 | 69.0 | 71.2 |  |  |  |  |
 | 0.012–0.023 | 89 | 70.7 | 69.6 | 71.9 |  |  |  |  |
 | 0.024–0.048 | 92 | 71.4 | 70.3 | 72.6 |  |  |  |  |
 | 0.049–0.491 | 92 | 71.3 | 70.1 | 72.5 |  |  |  |  |
 |  |  |  |  |  | 0.43 | 0.10 | 0.76 | 0.011 |
 | Log-transformed CRP |  |  |  |  | 0.42 | 0.07 | 0.78 | 0.019 |
Adjusted model 2b | 0.002–0.011 | 100 | 70.0 | 68.9 | 71.1 |  |  |  |  |
 | 0.012–0.023 | 89 | 70.8 | 69.6 | 71.9 |  |  |  |  |
 | 0.024–0.048 | 92 | 71.4 | 70.2 | 72.6 |  |  |  |  |
 | 0.049–0.491 | 92 | 71.3 | 70.1 | 72.4 |  |  |  |  |
 |  |  |  |  |  | 0.43 | 0.10 | 0.76 | 0.010 |
 | Log-transformed CRP |  |  |  |  | 0.42 | 0.06 | 0.79 | 0.021 |