Fig. 1

Effects of plocabulin on HUVEC cell morphology and microtubule mass by fluorescence microscopy. a HUVEC endothelial cells were cultured in the absence or presence of plocabulin 0.1 nM at different time intervals. Cells were then stained for α-tubulin (red) and nuclei (blue). b HUVEC endothelial cells were cultured in the absence or presence of increasing concentrations of plocabulin for 24 h. Representative images of each treatment conditions are shown