From: Frequency of the acquired resistant mutation T790 M in non-small cell lung cancer patients with active exon 19Del and exon 21 L858R: a systematic review and meta-analysis
Gender(n)
Age(n)
Smoking status(n)
OS* (months)
Man
Female
<70
≥70
Smoker
Non-smoker
T790 M(+)
73
133
84
22
46
136
41.6
T790 M(−)
81
125
102
27
45
127
30.3