Fig. 1

PFS and OS by ascites group. Progression-free survival by ascites group. Median PFS was shorter in patients with massive ascites (1.9 months; 95% CI, 1.7–2.1 months) than in patients with small or moderate ascites (3.2 months; 95% CI, 2.0–4.3 months; HR 0.57; 95% CI, 0.29–1.14; P = 0.11) or patients without ascites (5.1 months; 95% CI, 4.7–5.4 months; HR 0.65; 95% CI, 0.47–0.90; P = 0.01). Overall survival by ascites group. Median OS was shorter in patients with massive ascites (3.9 months; 95% CI, 3.2–4.5) than in patients with small or moderate ascites (9.6 months; 95% CI, 7.9–11.4 months; HR 0.41; 95% CI, 0.19–0.90; P = 0.026) or patients without ascites (11.3 months; 95% CI, 9.3–13.3 months; HR 0.54; 95% CI, 0.36–0.81; P = 0.003)