Table 3 Validation of Hypo1 by employing decoy set method
S. no | Parameters | Values |
|---|---|---|
1 | Total number of molecules in database (D) | 710 |
2 | Total number of actives in database (A) | 15 |
3 | Total number of hit molecules from the database (Ht) | 17 |
4 | Total number of active molecules in hit list (Ha) | 14 |
5 | % Yield of active [(Ha/Ht) | 82 |
6 | % Ratio of actives [(Ha/A) X 100] | 93 |
7 | Enrichment Factor (EF) | 44.17 |
8 | False negatives (A-Ha) | 1 |
9 | False Positives (Ht–Ha) | 3 |
10 | Goodness of fit score (GH) | 0.79 |