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Table 5 Evaluation of healthcare circuits for patients worldwide

From: Fertility preservation healthcare circuit and networks in cancer patients worldwide: what are the issues?

Location Authors, Date, Reference Study design Results
USA Zebrack et al., 2004, [40] 32 childhood cancer survivors Only 1/3 of patients had a discussion with the medical team on the risk of pregnancy during or after treatment.
USA Salih et al., 2015, [41] 222 female childhood cancers survivors [≤21 years] 31% patients older than 13 years had decreased ovarian reserve or have premature ovarian failure 33 patients had reproductive counseling prior to treatment, only 2 had counseling during or after treatment 1 patient had oocryopreservation prior to initiation of chemotherapy.
USA Kim et al., 2012, [42] 183 breast cancer patients 42% did not undergo FP treatment Women who had FP treatment were older, wealthier and had lower cancer stage
USA Letourneau et al., 2012, [43] 1041 women with cancer 61% were counseled on the risk of cancer treatment for fertility 4% of women pursued FP Disparities in access to FP were observed based on educational level, ethnicity and sexual orientation
France Huyghe et al., 2009, [44] 1000 cancer patients 20 to 30% would like to have more information on the potential risk of premature ovarian failure. 1/3 aged less than 50 years would have liked a fertility consultation before cancer treatment. 21% of women would definitely want to visit a reproductive health clinic in the next year.
France Bouhnik et al., 2014, [45] 4349 cancer survivors 2 years after diagnosis 31.9% of women under 45 had a parental project 2/3 under 45 did not have FP discussion prior to initiation of treatment 2.2% of women under 45 had access to cryopreservation of gametes
Germany Geue et al., 2013, [29] 149 cancer patients [18-45 years] 74% of patients wanted to have children at the time of diagnosis 50% of those who wanted a child needed supportive care concerning this issue 60% of the total sample had discussed fertility aspects with their oncologists and 20% with fertility specialists Men (56%) underwent fertility preservation more often than women (31%)
Sweden Armuand et al., 2012, [46] 484 Patients(men and women) 48% of women reported that they received information about treatment impact on fertility. 14% reported that they received information about FP. Only 2% underwent FP Large gender disparities in access to FP care
UK Corney and Swinglehurst, 2014, [47] 19 childless women aged below 45 withbreast cancer Only half were given the opportunity to pursue assisted reproductive techniques prior to chemotherapy.