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Table 3 Expected annual number of women with TNBC and gBRCA mutation in Germany

From: Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history

Age group Number of newly diagnosed BC cases in 2012 a % TNBC among all BC cases b % of TNBC w/o FH c Number of TNBC cases w/o FH % BRCA1/2 mutation carriers among TNBC cases w/o FH d Number of BRCA1/2 mutation carriers among TNBC cases without FH
< 40 2462 19.8 62.2 302 26.3 79
40–49 9757 10.5 56.8 580 12.1 70
50–59 15,059 9.0 65.8 891 6.9 61
60–69 16,497 7.0 71.9 835 3.8 32
70–79 15,420 6.9 71.9 768 2.1 16
  1. FH family history, BC breast cancer, TNBC triple-negative breast cancer
  2. aGerman Centre for Cancer Registry Data at the Robert Koch-Institute, Berlin, Germany
  3. bMunich Cancer Registry, MCR, Munich, Germany
  4. cCouch et al. [13]
  5. dpresent study