Table 1 Selected demographical and clinicopathological characteristics of study population (cases and controls)

Age (year)^b

63.1 ± 8.6

61.2 ± 9.0

0.001

BMI (kg/m²)^b

28.1 ± 5.0

27.3 ± 4.5

0.003

Sex

 Men

399 (62.9)

272 (58.5)

 Women

235 (37.1)

193 (41.5)

0.136

Race

 White

615 (97.0)

444 (95.5)

 Other

19 (3.0)

21 (5.0)

0.184

Family history of CRC

 Yes

62 (9.8)

35 (7.5)

 No

572 (90.2)

430 (92.5)

0.194

Level of education

 Lower than high school

302 (47.8)

140 (30.2)

 High-school graduate

100 (15.8)

74 (16.0)

 College

177 (28.0)

175 (37.7)

 Bachelor or higher

53 (8.4)

75 (16.1)

< 0.001

Smoking history

 Current

129 (20.3)

58 (12.5)

 Former

325 (51.3)

228 (49.4)

 Never

180 (28.4)

176 (38.1)

< 0.001

Reported screening procedure

 Yes

66 (10.4)

107 (23.0)

 No

568 (89.6)

358 (77.0)

< 0.001

Fruit intake (servings ^c/wk)^b

9.7 ± 8.3

10.9 ± 8.1

0.027

Total vitamin D intake (μg/d)^b

8.7 ± 6.4

10.2 ± 7.9

0.001

Total calcium intake (mg/d)^b

1019.8 ± 488.8

1097.1 ± 567.7

0.018

Milk (g/d)^b

287.1 ± 278.0

299.9 ± 295.5

0.465

Total dairy products (g/d)^b

364.5 ± 303.3

389.9 ± 340.0

0.200

Tumor location

 Colon

417 (65.8)

–

–

 Rectum

217 (34.2)

–

–

Stage at diagnosis

 I/II

288 (58.9)

–

–

 III/IV

201 (41.1)

–

–

Chemoradiotherapy

 Yes

106 (19.9)

–

–

 No

427 (80.1)

–

–

MSI status

 MSS/MSI-L

446 (88.0)

–

–

 MSI-H

61 (12.0)

–

–

BRAF mutation status

 Wild type

445 (89.2)

–

–

 BRAF mutant

54 (10.8)

–

–