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Table 2 Diagnostic performance of biomarkers alone for detection of lung cancer

From: Serum and blood based biomarkers for lung cancer screening: a systematic review

Test Evaluated EarlyCDT-lung MSC miR-test
Sensitivity 41% (95% CI: 29–53%) 87% (95%CI: N/A) 78% (95%CI: N/A)
Specificity 87% (95% CI: 86–89%) 81% (95% CI: 79–84%) 75% (95% CI: 72–78%)
PPV 11% (95% CI: 7–15%) 27% (95% CI: 21–32%) 10% (95% CI: 7–14%)
NPV 97% (95% CI: 97–98%) 98% (95% CI: N/A) 98% (95% CI: N/A)
Positive LR 3.19 4.67 3.09
Negative LR 0.68 0.16 0.30