Table 2 Diagnostic performance of biomarkers alone for detection of lung cancer
From: Serum and blood based biomarkers for lung cancer screening: a systematic review
Test Evaluated | EarlyCDT-lung | MSC | miR-test |
|---|---|---|---|
Sensitivity | 41% (95% CI: 29–53%) | 87% (95%CI: N/A) | 78% (95%CI: N/A) |
Specificity | 87% (95% CI: 86–89%) | 81% (95% CI: 79–84%) | 75% (95% CI: 72–78%) |
PPV | 11% (95% CI: 7–15%) | 27% (95% CI: 21–32%) | 10% (95% CI: 7–14%) |
NPV | 97% (95% CI: 97–98%) | 98% (95% CI: N/A) | 98% (95% CI: N/A) |
Positive LR | 3.19 | 4.67 | 3.09 |
Negative LR | 0.68 | 0.16 | 0.30 |