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Fig. 3 | BMC Cancer

Fig. 3

From: Exome sequencing of primary breast cancers with paired metastatic lesions reveals metastasis-enriched mutations in the A-kinase anchoring protein family (AKAPs)

Fig. 3

Expression profiles of the AKAP gene family in three different cohorts, tumors ordered by PAM50 subtype, genes are orderad by hierarchial clustering. a TCGA RNAseq expression profiles from primary tumors (n = 522). Genes are ordered by hierarchical clustering p < 0.0001 by ANOVA; q < 0.000072. Intrinsic subtype calls for the TCGA data were taken from the original manuscript [1]. b Risk Cohort microarray expression profiles from primary breast cancer tumors (n = 182). c Cohort 1 microarray expression profiles from metastatic lesions (n = 120)

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