Table 5 Accuracy of the GEP test and sentinel lymph node status
GEP Class | SLN status | |
|---|---|---|
% (95% CI) | % (95% CI) | |
RFS | ||
Sensitivity | 70% (62–78%) | 66% (57–74%) |
Specificity | 71% (67–76%) | 65% (58–71%) |
PPV | 48% (41–55%) | 52% (44–60%) |
NPV | 87% (82–90%) | 76% (69–82%) |
DMFS | ||
Sensitivity | 75% (66–83%) | 67% (57–76%) |
Specificity | 69% (65–74%) | 62% (55–68%) |
PPV | 40% (33–47%) | 42% (34–50%) |
NPV | 91% (87–94%) | 82% (76–88%) |
MSS | ||
Sensitivity | 85% (72–94%) | 79% (63–90%) |
Specificity | 64% (60–69%) | 58% (52–64%) |
PPV | 19% (14–25%) | 21% (15–28%) |
NPV | 98% (95–99%) | 95% (91–98%) |