|  | Means ± Standard Deviation |  | |
---|---|---|---|---|
 | Frequency | 1st month | 12th month | P value |
Functional scales | ||||
 Body image | 669 | 81,88 ± 23,32 | 85,52 ± 20,50 | < 0,001 |
 Sexual functional | 462 | 76,69 ± 23,68 | 69,84 ± 22,19 | < 0,001 |
 Sexual enjoyment | 244 | 55,60 ± 29,64 | 53,14 ± 30,30 | < 0,001 |
 Future Perspective | 662 | 39,78 ± 37,23 | 46,68 ± 38,13 | < 0,001 |
Symptom scales | ||||
 systemic therapy side effects | 685 | 16,86 ± 17,04 | 17,16 ± 17,77 | < 0,001 |
 Breast Symptoms | 650 | 18,71 ± 19,97 | 15,04 ± 19,02 | < 0,001 |
 Arm Symptoms | 661 | 22,52 ± 21,16 | 18,92 ± 19,39 | < 0,001 |
 Upset by hair loss | 151 | 20,97 ± 27,65 | 22,96 ± 26,72 | 0,003 |