Fig. 4

ExmiR-451a was correlated with the Clinical Features of IPMN, and might be able to diagnose high risk cases. a The correlation between the expression levels of the three ExmiRs and the Fukuoka criteria. There were no significant differences in the expression of ExmiR-191, ExmiR-21 or ExmiR-451a between FN, WF and HRS. However, the ExmiR-451a level appeared to be gradually increasing (p = 0.0602). b The association between the expressions of three ExmiRs and clinical features, gender, age, cyst diameter, mural nodules, main pancreatic dilatation and Progression of cyst diameter, in IPMN group was assessed. The ExmiR expressions were plotted and those median with interquartile range was also shown. The expression of ExmiR-451a was significantly higher in the patients with mural nodules. Although there were no other significant differences, ExmiR-451a also seemed to be high with a large cyst diameter and main pancreatic dilatation