Fig. 3

ExmiR-191, ExmiR-21, and ExmiR-451a were good diagnostic markers for IPMN and early-stage PC. a The levels of CEA (left) and CA19–9 (right) were plotted (median with interquartile range was also shown). CA19–9 was significantly higher in the PC group than in the control or IPMN groups. b The ROC analysis between control and IPMN was shown. The AUC and diagnostic accuracy of three ExmiRs were clearly superior to traditional markers. c The ROC analysis between control and early stage of PC including only patients with stage I or IIa showed. The diagnostic accuracy of three ExmiRs were superior to CEA, and tended to be better than CA19–9. d The ROC analysis between the control group and the advanced-stage PC group (stage ≥IIb). The AUC values and accuracy of the three ExmiRs were superior to CEA, but they were not as useful as CA19–9