|
Metropolitan
|
Nonmetropolitan
|
Model 1: Not adjusted for smoking
|
Model 2: Adjusted for smoking
|
---|
|
Rate
|
Count
|
Person-years
|
Rate
|
Count
|
Person-years
|
P-value
|
P-value
|
---|
Overall incidence
|
29.7
|
8302
|
40,106,205
|
34.8
|
1630
|
5,297,867
|
<.0001*
|
0.19
|
Stage
|
Localized
|
5.2
|
1462
|
40,106,205
|
6.0
|
285
|
5,297,867
|
0.02*
|
0.83
|
Regional
|
6.3
|
1792
|
40,106,205
|
7.2
|
336
|
5,297,867
|
0.04*
|
0.15
|
Distant
|
15.4
|
4317
|
40,106,205
|
16.7
|
784
|
5,297,867
|
0.02*
|
0.02*
|
Unstaged
|
2.7
|
731
|
40,106,205
|
4.9
|
225
|
5,297,867
|
< 0.0001*
|
< 0.0001*
|
Sex
|
Male
|
39.5
|
4963
|
20,073,510
|
45.7
|
1004
|
2,662,232
|
< 0.0001*
|
0.24
|
Female
|
21.9
|
3339
|
20,032,695
|
25.4
|
626
|
2,635,635
|
0.0003*
|
0.46
|
- Rates adjusted to the 2000 United States standard population. Person-years shown here are not age-adjusted. *Indicate p-values < 0.05 are significant