Fig. 7
![Fig. 7](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs12885-018-3993-6/MediaObjects/12885_2018_3993_Fig7_HTML.gif)
A Model depicting the role of CCN5 on leptin-induced cell viability, EMT, cell migration and Stemness. Leptin blocks CCN5 expression via activating JAK/ AKT /STAT3-signaling in luminal (ER-positive) BC cells to promote cell viability and aggressive phenotypes of these cells