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Fig. 4 | BMC Cancer

Fig. 4

From: Variant isoforms of CD44 involves acquisition of chemoresistance to cisplatin and has potential as a novel indicator for identifying a cisplatin-resistant population in urothelial cancer

Fig. 4

Intracellular GSH levels in T24 and T24PR cells and their ROS production by CDDP. a Intracellular GSH levels in T24 and T24PR cells. Intracellular GSH levels were significantly higher in T24PR cells than in T24 cells (#; p < 0.001). b Intracellular ROS production in T24 and T24PR cells after exposure to various concentrations of CDDP (0 to 10 μM). In T24 cells, significant ROS production was observed at CDDP concentrations of 2 μM or higher as compared to vehicle control. In T24PR cells, significant ROS production was observed only at a CDDP concentration of 10 μM. †; p < 0.01, #; p < 0.001

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