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Table 3 Anticancer medicines prescribed to study participants

From: Availability of anticancer medicines in public and private sectors, and their affordability by low, middle and high-income class patients in Pakistan

Sr. No Medicine and Dose ATC Code f (n = 9893) %a Trend OB Per month cost LPG Per month cost
1 Anastrozole 1 mg tab L02BG03 71 (1.6) Low Anastrozole (Novartis) 6000 Femizet (Atco) 5130
2 Bicalutamide 50 mg tab L02BB03 109 (2.5) Low Casodex (ICI) 12,642 Calutide (A. J. Mirza) 4308
3 Bleomycin 15 mg inj L01 DC01 42 (1.0) Low Bleomycin (Pharmedic) 9960 Bemocin (Atco) 8000
4 Capecitabine 500 mg tab L01 BC06 258 (5.9) Medium Xeloda (Roche) 25,000 NA NA
5 Carboplatin 150 mg inj L01XA02 206 (4.7) Low Carpsol (Pfizer) 6681 Carboplatin (Atco) 3000
6 Cisplatin 50 mg inj L01XA01 2177 (49.5) High Cisplasol (Pfizer) 3099 Platosin (Pharmachemie) 1750
7 Cyclophosphamide 500 mg inj L01AA01 877 (19.9) High Cyclomide (Pharmedic) 5625 Cyclophosphamide (S. Ejazuddin) 3000
8 Cyproterone Acetate 50 mg tab G03HA01 66 (1.5) Low Androcur (Bayer) 3588 NA NA
9 Cytarabine 100 mg inj L01 BC01 342 (7.8) Medium Cytosar (Pfizer) 2700 Cytarabine (Highnoon) 1785
10 Dacarbazine 200 mg inj L01AX04 74 (1.7) Low Duticin (Al-Habib) 2700 Darbazine (Pharmedic) 2500
11 Dactinomycin 0.5 mg inj L01DA01 71 (1.6) Low Dactinomycin (Al-Habib) 28,616 Dactinofin (Pharmedic) 23,520
12 Daunomycin 20 mg inj L01DB02 111 (2.5) Low Daunoblastina (Pfizer) 6750 D-Blastin (Pharmedic) 5700
13 Docetaxil 80 mg inj L01CD02 18 (0.4) Low Taxotere (Sanofi aventis) 76,000 Docekebir (Oncogene) 74,400
14 Doxorubicin 50 mg inj L01DB01 385 (8.8) Medium Adriblastina (Pfizer) 4495 Doxorubicin (Al- Habib) 3170
15 Epirubicin 50 mg inj L01DB03 427 (9.7) Medium Farmorubicin (Pfizer) 13,270 Anthracin (Atco) 9510
16 Etoposide 100 mg inj L01CB01 1137 (25.8) High Etoposide (Pfizer) 7150 Lymphoside (CCL) 4950
17 Fludarabine phosphate 50 mg inj L01BB05 180 (4.1) Low Fludara (Sanofi aventis) 66,313 Fludakebir (Oncogene) 46,400
18 Flourouracil 500 mg inj L01 BC02 502 (11.4) High Pharmauracil (Pharmedic) 1944 Secouracil (S. Ejazuddin) 176
19 Gemicitabine 1 g inj L01 BC05 685 (15.6) High Gemzar (Eli lilly) 64,020 Gemita (Atco) 41,650
20 Hydroxyurea 500 mg cap L01XX05 43 (1.0) Low Hydra (Medinet) 1200 Hydrine (Al-Habib) 1168
21 Ifosfamide I gminj L01AA06 71 (1.6) Low Ifosfamin (Pharmedic) 12,000 Fosfamin (CCL) 12,000
22 Imatinibmesylate 400 mg tab L01XE01 67 (1.5) Low Glivec (Novartis) 140,000 NA NA
23 Irinotecan 100 mg inj L01XX19 181 (4.1) Low Campto (Pfizer) 133,480 Irinocan (Pharmedic) 71,250
24 Lapatinib 250 mg tab L01XE07 43 (1.0) Low Tykerb (GSK) 201,650 NA NA
25 Letrozole 2.5 mg tab L02BG04 71 (1.6) Low Femara (Novartis) 8720 Letara (A.J. Mirza) 5100
26 Mercaptopurine 50 mg tab L01BB02 111 (2.5) Low Mercaprine (Pharmedia) 741 Purinetone (Al- Habib) 630
27 Methotrexate 10 mg tab L01BA01 72 (1.6) Low Emthexate (Pharmachemie) 817 Unitrexate (Al-Habib) 410
28 Mitomycin 10 mg inj L01 DC03 71 (1.6) Low Mitocin (Pharmedic) 2256 Mitomycin (S.Ejazuddin) 232
29 Mitoxantrone 20 mg inj L01DB07 43 (1.0) Low Mitoxantrona (Atco) 4000 NA NA
30 Nilotinib 200 mg cap L01XE08 43 (1.0) Low Tasigna (Novartis) 456,000 NA NA
31 Oxalplatin 100 mg inf L01XA03 288 (6.5) Medium Oxitan (Atco) 60,000 Eloxatin (Sanofi aventis) 52,500
32 Paclitaxel 260 mg inf L01CD01 71 (1.6) Low Intaxel (Atco) 34,600 Paclixil (A.J. Mirza) 34,600
33 Pazopanib 400 mg tab L01XE11 67 (1.5) Low Votrient (GSK) 176,666 NA NA
34 Sorafenib 200 mg tab L01XE05 43 (1.0) Low Nexavar (Bayer) 465,600 NA NA
35 Sunitinib 50 mg cap L01XE04 67 (1.5) Low Sutent (Pfizer) 392,640 NA NA
36 Tamoxifen 20 mg tab L02BA01 71 (1.6) Low Tamox (Pharmedic) 600 Tamooxe (Al-Habib) 450
37 Thalidomide 100 mg cap L04AX02 43 (1.0) Low Thalido(Atco) 6000 NA NA
38 Vinblastine 10 mg inj L01CA01 42 (1.0) Low Velbastine (Al-Habib) 4165 Vinblas (Pharmedic) 2800
39 Vincristine 2 mg inj L01CA02 522 (11.9) High Pharmacristine (Pharmedic) 1580 Vincristine Gador (Seignior) 1124
40 Vinorelbine 50 mg inj L01CA04 71 (1.6) Low Vinelbine (Atco) 33,480 Vinkebir (Oncogene) 33,480
  1. aPercentages given with respect to the total sample size of patients. ATC = Anatomical Therapeutic Chemical; f = Frequency; OB = Originator brand; LPG = Lowest price generic; NA = Not available. Note: The specialists were reluctant to prescribe medicines such as bevacizumab, cabazitaxel, cetuximab, erlotinib, idarubicin, pemetrexed, rituximab, ruxolitinib, temozolomide, topotecan, and trastuzumab due to their much higher prices