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Table 2 Histologic types and genetic characteristics of the cancers

From: Nine primary malignant neoplasms-involving the esophagus, stomach, colon, rectum, prostate, and external ear canal-without microsatellite instability: a case report

Organ Histology Immunohistochemistry Mutation MSI
p53 Nuclear β-catenin KRAS BRAF
Esophagus 1 SCC + Wt Wt MSS
Esophagus 2 SCC Wt Wt MSS
Stomach 1 AC + Wt Wt MSS
Ear canal SCC Wt Wt MSS
Esophagus 3 SCC Wt Wt MSS
Rectum AC + + G12C Wt MSS
Stomach 2 AC G12C Wt MSS
Prostate AC Wt Wt MSS
Colon AC + G13 V Wt MSS
  1. The histologic, immunohistochemical (p53, β-catenin), and mutational analysis (KRAS, BRAF, and microsatellite status) characteristics of surgically and endoscopically removed tumor tissues from a man diagnosed with nine metachronous primary malignant lesions
  2. SCC, squamous cell carcinoma; AC, adenocarcinoma; Wt, wild type; MSI, microsatellite instability; MSS, microsatellite stable