Outcome | Control | Intervention | ∆ = Intervention - Control | ||||||
---|---|---|---|---|---|---|---|---|---|
Mean | SEa | n (or P-value)b | Mean | SE | n (or P-value) | ∆ | SEDc | P_value | |
ZBIe | |||||||||
 BL | 18.05 | 1.17 | 108 | 18.99 | 1.17 | 107 | 0.95 | 1.65 | 0.568 |
 M1 | 17.81 | 1.31 | 73 | 19.39 | 1.27 | 82 | 1.58 | 1.82 | 0.386 |
 M6 | 17.20 | 1.33 | 69 | 18.46 | 1.31 | 73 | 1.26 | 1.87 | 0.500 |
 M1-BL | −0.24 | 1.13 | 0.835 | 0.40 | 1.09 | 0.713 |  |  |  |
 M6-BL | −0.85 | 1.16 | 0.464 | −0.53 | 1.14 | 0.639 |  |  |  |
 M6-M1 | −0.61 | 1.23 | 0.620 | −0.93 | 1.16 | 0.422 |  |  | 0.921d |
CRAf Total | |||||||||
 BL | 30.07 | 0.44 | 108 | 30.80 | 0.44 | 105 | 0.73 | 0.62 | 0.243 |
 M1 | 29.80 | 0.50 | 73 | 29.58 | 0.49 | 80 | −0.22 | 0.70 | 0.750 |
 M6 | 29.76 | 0.52 | 66 | 29.66 | 0.51 | 70 | −0.09 | 0.73 | 0.897 |
 M1-BL | −0.27 | 0.49 | 0.578 | −1.22 | 0.48 | 0.012 |  |  |  |
 M6-BL | −0.31 | 0.51 | 0.538 | −1.13 | 0.50 | 0.025 |  |  |  |
 M6-M1 | −0.04 | 0.54 | 0.940 | 0.09 | 0.52 | 0.867 |  |  | 0.320 |
SCNS-P&Cg (√ transformed) | |||||||||
 BL | 1.14 | 0.13 | 108 | 1.63 | 0.13 | 108 | 0.49 | 0.18 | 0.007 |
 M1 | 1.01 | 0.15 | 75 | 0.92 | 0.14 | 83 | −0.09 | 0.20 | 0.659 |
 M6 | 0.41 | 0.15 | 68 | 0.53 | 0.15 | 73 | 0.12 | 0.21 | 0.577 |
 M1-BL | −0.13 | 0.15 | 0.401 | −0.71 | 0.15 | <0.001 |  |  |  |
 M6-BL | −0.73 | 0.16 | <0.001 | −1.10 | 0.16 | <0.001 |  |  |  |
 M6-M1 | −0.60 | 0.17 | 0.001 | −0.39 | 0.16 | <0.001 |  |  | 0.023 |
CES-Dh Total | |||||||||
 BL | 11.46 | 0.91 | 107 | 13.24 | 0.91 | 108 | 1.79 | 1.29 | 0.168 |
 M1 | 10.98 | 1.02 | 75 | 12.32 | 0.99 | 82 | 1.34 | 1.42 | 0.347 |
 M6 | 10.62 | 1.04 | 68 | 12.04 | 1.02 | 73 | 1.42 | 1.46 | 0.334 |
 M1-BL | −0.48 | 0.89 | 0.592 | −0.93 | 0.85 | 0.280 |  |  |  |
 M6-BL | −0.83 | 0.92 | 0.369 | −1.20 | 0.89 | 0.180 |  |  |  |
 M6-M1 | −0.36 | 0.97 | 0.715 | −0.27 | 0.92 | 0.765 |  |  | 0.926 |
heiQi Dom1 HDB | |||||||||
 BL | 2.90 | 0.07 | 107 | 2.83 | 0.07 | 108 | −0.06 | 0.10 | 0.548 |
 M1 | 3.05 | 0.08 | 75 | 2.81 | 0.08 | 82 | −0.24 | 0.11 | 0.034 |
 M6 | 2.96 | 0.08 | 68 | 2.92 | 0.08 | 73 | −0.04 | 0.12 | 0.749 |
 M1-BL | 0.15 | 0.07 | 0.026 | −0.03 | 0.07 | 0.680 |  |  |  |
 M6-BL | 0.06 | 0.07 | 0.379 | 0.09 | 0.07 | 0.202 |  |  |  |
 M6-M1 | −0.09 | 0.07 | 0.224 | 0.11 | 0.07 | 0.105 |  |  | 0.080 |
heiQ Dom2 PAEL | |||||||||
 BL | 3.15 | 0.05 | 108 | 3.05 | 0.05 | 108 | −0.10 | 0.07 | 0.157 |
 M1 | 3.18 | 0.06 | 75 | 3.02 | 0.05 | 82 | −0.17 | 0.08 | 0.035 |
 M6 | 3.22 | 0.06 | 68 | 3.06 | 0.06 | 73 | −0.16 | 0.08 | 0.053 |
 M1-BL | 0.03 | 0.05 | 0.464 | −0.03 | 0.05 | 0.509 |  |  |  |
 M6-BL | 0.07 | 0.05 | 0.166 | 0.01 | 0.05 | 0.782 |  |  |  |
 M6-M1 | 0.03 | 0.05 | 0.518 | 0.04 | 0.05 | 0.377 |  |  | 0.564 |
heiQ Dom3 ED | |||||||||
 BL | 1.70 | 0.06 | 106 | 1.78 | 0.06 | 106 | 0.09 | 0.08 | 0.303 |
 M1 | 1.73 | 0.07 | 75 | 1.95 | 0.06 | 82 | 0.22 | 0.09 | 0.015 |
 M6 | 1.68 | 0.07 | 67 | 1.91 | 0.07 | 73 | 0.23 | 0.10 | 0.016 |
 M1-BL | 0.03 | 0.06 | 0.653 | 0.17 | 0.06 | 0.005 |  |  |  |
 M6-BL | −0.02 | 0.06 | 0.766 | 0.13 | 0.06 | 0.036 |  |  |  |
 M6-M1 | −0.05 | 0.07 | 0.488 | −0.04 | 0.06 | 0.537 |  |  | 0.144 |
heiQ Dom4 SMI | |||||||||
 BL | 3.17 | 0.04 | 106 | 3.16 | 0.04 | 108 | −0.01 | 0.06 | 0.859 |
 M1 | 3.13 | 0.05 | 75 | 3.07 | 0.04 | 82 | −0.06 | 0.06 | 0.354 |
 M6 | 3.22 | 0.05 | 68 | 3.14 | 0.05 | 73 | −0.08 | 0.07 | 0.209 |
 M1-BL | −0.04 | 0.04 | 0.418 | −0.08 | 0.04 | 0.047 |  |  |  |
 M6-BL | 0.06 | 0.05 | 0.199 | −0.01 | 0.04 | 0.749 |  |  |  |
 M6-M1 | 0.09 | 0.05 | 0.051 | 0.07 | 0.05 | 0.124 |  |  | 0.489 |
heiQ Dom5 CAA | |||||||||
 BL | 3.38 | 0.05 | 105 | 3.31 | 0.05 | 104 | −0.07 | 0.06 | 0.268 |
 M1 | 3.30 | 0.05 | 75 | 3.20 | 0.05 | 82 | −0.11 | 0.07 | 0.124 |
 M6 | 3.38 | 0.05 | 67 | 3.25 | 0.05 | 72 | −0.13 | 0.07 | 0.083 |
 M1-BL | −0.08 | 0.05 | 0.117 | −0.12 | 0.05 | 0.016 |  |  |  |
 M6-BL | 0.00 | 0.05 | 0.980 | −0.06 | 0.05 | 0.256 |  |  |  |
 M6-M1 | 0.08 | 0.05 | 0.145 | 0.06 | 0.05 | 0.248 |  |  | 0.701 |
heiQ Dom6 STA | |||||||||
 BL | 3.17 | 0.04 | 102 | 3.15 | 0.04 | 103 | −0.02 | 0.06 | 0.794 |
 M1 | 3.04 | 0.05 | 74 | 3.01 | 0.05 | 83 | −0.04 | 0.07 | 0.560 |
 M6 | 3.17 | 0.05 | 66 | 3.09 | 0.05 | 73 | −0.08 | 0.07 | 0.262 |
 M1-BL | −0.12 | 0.05 | 0.015 | −0.15 | 0.05 | 0.002 |  |  |  |
 M6-BL | 0.00 | 0.05 | 0.997 | −0.06 | 0.05 | 0.202 |  |  |  |
 M6-M1 | 0.12 | 0.05 | 0.026 | 0.08 | 0.05 | 0.108 |  |  | 0.672 |
heiQ Dom7 SIS | |||||||||
 BL | 3.23 | 0.05 | 106 | 3.12 | 0.05 | 104 | −0.11 | 0.07 | 0.114 |
 M1 | 3.08 | 0.05 | 75 | 2.98 | 0.05 | 83 | −0.10 | 0.08 | 0.212 |
 M6 | 3.24 | 0.06 | 68 | 3.05 | 0.06 | 73 | −0.19 | 0.08 | 0.016 |
 M1-BL | −0.15 | 0.05 | 0.003 | −0.13 | 0.05 | 0.006 |  |  |  |
 M6-BL | 0.01 | 0.05 | 0.778 | −0.07 | 0.05 | 0.191 |  |  |  |
 M6-M1 | 0.16 | 0.05 | 0.003 | 0.07 | 0.05 | 0.193 |  |  | 0.392 |
heiQ Dom8 HSN | |||||||||
 BL | 3.27 | 0.05 | 105 | 3.17 | 0.05 | 103 | −0.10 | 0.07 | 0.153 |
 M1 | 3.23 | 0.05 | 75 | 3.07 | 0.05 | 83 | −0.16 | 0.08 | 0.034 |
 M6 | 3.39 | 0.06 | 67 | 3.15 | 0.05 | 73 | −0.24 | 0.08 | 0.003 |
 M1-BL | −0.04 | 0.05 | 0.409 | −0.10 | 0.05 | 0.032 |  |  |  |
 M6-BL | 0.12 | 0.05 | 0.015 | −0.02 | 0.05 | 0.753 |  |  |  |
 M6-M1 | 0.16 | 0.05 | 0.002 | 0.09 | 0.05 | 0.086 |  |  | 0.144 |
HLQj S1 | |||||||||
 BL | 3.24 | 0.05 | 105 | 3.11 | 0.05 | 103 | −0.13 | 0.07 | 0.083 |
 M1 | 3.25 | 0.06 | 73 | 3.15 | 0.06 | 83 | −0.10 | 0.08 | 0.208 |
 M6 | 3.30 | 0.06 | 67 | 3.17 | 0.06 | 73 | −0.13 | 0.08 | 0.109 |
 M1-BL | 0.01 | 0.05 | 0.913 | 0.03 | 0.05 | 0.492 |  |  |  |
 M6-BL | 0.06 | 0.05 | 0.220 | 0.06 | 0.05 | 0.239 |  |  |  |
 M6-M1 | 0.06 | 0.05 | 0.288 | 0.03 | 0.05 | 0.604 |  |  | 0.892 |
HLQ S2 | |||||||||
 BL | 3.15 | 0.04 | 106 | 3.10 | 0.04 | 105 | −0.05 | 0.06 | 0.388 |
 M1 | 3.15 | 0.05 | 74 | 3.09 | 0.05 | 83 | −0.06 | 0.07 | 0.392 |
 M6 | 3.23 | 0.05 | 67 | 3.19 | 0.05 | 73 | −0.04 | 0.07 | 0.552 |
 M1-BL | −0.01 | 0.05 | 0.880 | −0.01 | 0.04 | 0.785 |  |  |  |
 M6-BL | 0.08 | 0.05 | 0.107 | 0.09 | 0.05 | 0.058 |  |  |  |
 M6-M1 | 0.08 | 0.05 | 0.097 | 0.10 | 0.05 | 0.034 |  |  | 0.970 |
HLQ S3 | |||||||||
 BL | 2.96 | 0.05 | 107 | 2.89 | 0.05 | 105 | −0.07 | 0.07 | 0.282 |
 M1 | 2.95 | 0.05 | 74 | 2.91 | 0.05 | 83 | −0.04 | 0.07 | 0.616 |
 M6 | 2.99 | 0.05 | 67 | 2.91 | 0.05 | 72 | −0.08 | 0.08 | 0.286 |
 M1-BL | −0.02 | 0.05 | 0.758 | 0.02 | 0.05 | 0.692 |  |  |  |
 M6-BL | 0.03 | 0.05 | 0.558 | 0.02 | 0.05 | 0.695 |  |  |  |
 M6-M1 | 0.05 | 0.05 | 0.405 | 0.00 | 0.05 | 0.987 |  |  | 0.815 |
HLQ S4 | |||||||||
 BL | 3.19 | 0.05 | 106 | 3.04 | 0.05 | 105 | −0.16 | 0.07 | 0.019 |
 M1 | 3.12 | 0.05 | 74 | 3.02 | 0.05 | 83 | −0.10 | 0.07 | 0.166 |
 M6 | 3.23 | 0.05 | 68 | 3.04 | 0.05 | 73 | −0.19 | 0.07 | 0.010 |
 M1-BL | −0.07 | 0.05 | 0.119 | −0.02 | 0.04 | 0.721 |  |  |  |
 M6-BL | 0.04 | 0.05 | 0.382 | 0.00 | 0.05 | 0.940 |  |  |  |
 M6-M1 | 0.11 | 0.05 | 0.024 | 0.02 | 0.05 | 0.682 |  |  | 0.381 |
HLQ S5 | |||||||||
 BL | 2.90 | 0.05 | 104 | 2.86 | 0.05 | 104 | −0.04 | 0.07 | 0.587 |
 M1 | 2.89 | 0.06 | 73 | 2.88 | 0.05 | 83 | −0.01 | 0.08 | 0.878 |
 M6 | 2.95 | 0.06 | 67 | 2.91 | 0.06 | 73 | −0.04 | 0.08 | 0.587 |
 M1-BL | −0.01 | 0.05 | 0.802 | 0.01 | 0.05 | 0.788 |  |  |  |
 M6-BL | 0.05 | 0.05 | 0.372 | 0.04 | 0.05 | 0.412 |  |  |  |
 M6-M1 | 0.06 | 0.06 | 0.282 | 0.03 | 0.05 | 0.578 |  |  | 0.903 |
HLQ S6 | |||||||||
 BL | 4.22 | 0.06 | 106 | 4.23 | 0.06 | 104 | 0.01 | 0.09 | 0.863 |
 M1 | 4.19 | 0.07 | 74 | 4.28 | 0.07 | 83 | 0.10 | 0.10 | 0.322 |
 M6 | 4.28 | 0.07 | 68 | 4.18 | 0.07 | 73 | −0.10 | 0.10 | 0.331 |
 M1-BL | −0.03 | 0.07 | 0.626 | 0.05 | 0.07 | 0.470 |  |  |  |
 M6-BL | 0.06 | 0.07 | 0.388 | −0.05 | 0.07 | 0.454 |  |  |  |
 M6-M1 | 0.09 | 0.07 | 0.207 | −0.10 | 0.07 | 0.158 |  |  | 0.168 |
HLQ S7 | |||||||||
 BL | 4.14 | 0.06 | 104 | 4.12 | 0.06 | 104 | −0.03 | 0.09 | 0.772 |
 M1 | 4.10 | 0.07 | 73 | 4.21 | 0.07 | 83 | 0.11 | 0.10 | 0.259 |
 M6 | 4.19 | 0.07 | 68 | 4.14 | 0.07 | 73 | −0.05 | 0.10 | 0.629 |
 M1-BL | −0.04 | 0.06 | 0.498 | 0.09 | 0.06 | 0.143 |  |  |  |
 M6-BL | 0.05 | 0.07 | 0.488 | 0.02 | 0.06 | 0.717 |  |  |  |
 M6-M1 | 0.09 | 0.07 | 0.200 | −0.07 | 0.06 | 0.306 |  |  | 0.192 |
HLQ S8 | |||||||||
 BL | 4.15 | 0.06 | 105 | 4.13 | 0.06 | 104 | −0.03 | 0.09 | 0.774 |
 M1 | 4.08 | 0.07 | 73 | 4.18 | 0.07 | 83 | 0.09 | 0.10 | 0.341 |
 M6 | 4.19 | 0.07 | 68 | 4.13 | 0.07 | 73 | −0.05 | 0.10 | 0.614 |
 M1-BL | −0.07 | 0.07 | 0.333 | 0.05 | 0.07 | 0.473 |  |  |  |
 M6-BL | 0.03 | 0.07 | 0.657 | 0.01 | 0.07 | 0.928 |  |  |  |
 M6-M1 | 0.10 | 0.08 | 0.192 | −0.04 | 0.07 | 0.559 |  |  | 0.336 |
HLQ S9 | |||||||||
 BL | 4.31 | 0.05 | 104 | 4.30 | 0.05 | 104 | −0.01 | 0.08 | 0.916 |
 M1 | 4.27 | 0.06 | 74 | 4.37 | 0.06 | 83 | 0.10 | 0.08 | 0.234 |
 M6 | 4.32 | 0.06 | 68 | 4.37 | 0.06 | 73 | 0.05 | 0.09 | 0.563 |
 M1-BL | −0.04 | 0.06 | 0.512 | 0.07 | 0.06 | 0.197 |  |  |  |
 M6-BL | 0.00 | 0.06 | 0.948 | 0.06 | 0.06 | 0.279 |  |  |  |
 M6-M1 | 0.04 | 0.06 | 0.504 | −0.01 | 0.06 | 0.884 |  |  | 0.390 |