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Fig. 4 | BMC Cancer

Fig. 4

From: CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension

Fig. 4

Differential gene expression of LCN2 in thyroid tumours and normal tissues. Gene expression was measured in follicular thyroid adenoma (FTA), follicular thyroid cancer (FTC), follicular variant of papillary thyroid carcinoma (FVPTC), papillary thyroid carcinoma (PTC), normal thyroid tissues and thyroid cancer cell lines by real-time quantitative PCR. Histogram showing the gene expression of each sample ordered by expression levels (a). Box plot representation (median and Tukey whiskers) showing gene expression of each subgroup of thyroid tumours – FTA, FTC, FVPTC and PTC (b). Gene expression of the thyroid cancer cell lines (c). Gene expression was calibrated by the pool of normal thyroid tissues. Statistically significant values: *P = 0.013 **P < 0.001

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