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Fig. 2 | BMC Cancer

Fig. 2

From: CRABP1, C1QL1 and LCN2 are biomarkers of differentiated thyroid carcinoma, and predict extrathyroidal extension

Fig. 2

Receiver Operating Characteristics (ROC) curves for gene expression of potential biomarkers in thyroid cancers. ROC curves for gene expression of individual and combined potential biomarkers in differentiated thyroid cancers (DTC) versus normal thyroid tissues and DTC versus FTA. The area under the ROC curve (AUC) represents the accuracy of the individual and combined potential biomarkers for distinguishing differentiated thyroid cancers (DTC) from normal thyroid tissue samples or follicular thyroid adenoma (FTA) (a-d). DTC versus normal thyroid for individual (a) and combined (c) potential biomarkers with gain (C1QL1and LCN2) and loss (CRABP1 and CILP) of gene expression in cancer. DTC versus FTA for individual (b) and combined (d) potential biomarkers with gain (C1QL1 and LCN2) and loss (CRABP1 and CILP) of gene expression in cancer. Asymptotic significance, standard error and 95% confidence interval measurements for all values can be found in Additional file 10: Table S5

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