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Table 3 Factors associated with CD105/CD31 expression ratio – univariable analysis

From: Evaluation of Endoglin (CD105) expression in pediatric rhabdomyosarcoma

Variables

Number of patients (%)

Univariable Analysis

Coefficient

IC

P value

  ≥ 1 < 10 (ref)

21 (70)

–

–

–

  < 1 ≥ 10

9 (30)

− 0.10

− 0.77;0.56

0.757

Histology

 ARMS (ref)

12 (40)

–

–

–

 ERMS

18 (60)

− 0.49

− 0.89;-0.08

0.019

Tumor size

  ≤ 5 cm (ref)

10 (33)

–

–

–

  > 5 cm

20 (77)

− 0.28

− 0.83;0.27

0.313

Primary site (location)

 Favorable (ref)

12 (40)

–

–

–

 Unfavorable

18 (60)

0.01

− 0.45;0.47

0.962

COG Risk Group

 Low (ref)

8 (27)

–

–

–

 Intermediate

16 (53)

0.13

− 0.53;0.79

0.682

 High

6 (20)

− 0.01

− 0.84;0.81

0.977

VEGF score

 1–2 (ref)

19 (63)

–

–

–

 3–4

11 (37)

0.41

− 0.04;0.85

0.072

Status

 Alive (ref)

22 (73)

–

–

–

 Dead

8 (27)

0.53

0.10;

0.95

0.016

  1. (Ref Reference, IC interval confidence, COG Children’s Oncology Group, ERMS embryonal rhabdomyosarcoma, ARMS alveolar rhabdomyosarcoma, VEGF Vascular Endothelial Growth Factor, CD105 Endoglin). In boldface the values statistically significant