Fig. 5

Overexpression of miR-200a was associated with poor response to preoperative chemotherapy and poor prognosis in patients with breast cancers. a Relationship between miR-200a expression and response to preoperative chemotherapy in patients with breast cancer. 72 patients with breast cancer who received preoperative chemotherapy followed by surgery were divided into two groups according to the chemotherapy response. The means of the two groups were significantly different from each other (t-test, p = 0.0021). b Kaplan-Meier curves of disease free survival rates of 110 patients with breast cancer who had definitive surgical treatment of their primary tumors according to miR-200a expression. The optimal cut-off point was determined by X-tile program. PR: partial response, SD: stable disease, PD: progressive disease