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Table 4 Univariate and multivariate logistic regression analysis of patient and tumour factors associated with the probability of undergoing a liver intervention for CRCLM

From: Colorectal cancer liver metastases – a population-based study on incidence, management and survival

 

Univariate analysisa

Multivariate analysisa

Odds ratio (95% CI)

P

Odds ratio (95% CI)

P

Patient factors

Age (years)

  > 68

1.00 (reference)

 

1.00 (reference)

 

  ≤ 68

2.93 (1.63–5.24)

<0.001

2.71 (1.29–5.69)

0.009

Sex

 Female

1.00 (reference)

 

1.00 (reference)

 

 Male

1.52 (0.86–2.69)

0.146

0.94 (0.45–1.98)

0.879

Tumour factors

Tumour stageb

 T1 or T2

1.00 (reference)

 

1.00 (reference)

 

 T3 or T4

0.31 (0.10–0.97)

0.045

0.16 (0.03–0.87)

0.035

Nodal stageb

 N0

1.00 (reference)

 

1.00 (reference)

 

 N1 or N2

0.31 (0.16–0.62)

0.001

0.72 (0.31–1.67)

0.440

Time of detection

 Metachronous

1.00 (reference)

 

1.00 (reference)

 

 Synchronous

0.41 (0.24–0.72)

0.002

1.20 (0.57–2.55)

0.626

No of liver metastases

 1–2

1.00 (reference)

 

1.00 (reference)

 

 3–4

0.70 (0.32–1.56)

0.387

0.90 (0.33–2.46)

0.844

 ≥ 5

0.06 (0.02–0.14)

<0.001

0.07 (0.03–0.19)

<0.001

Tumour origin

 Right-sided

1.00 (reference)

 

1.00 (reference)

 

 Left-sidedc

2.67 (1.31–5.44)

0.007

1.92 (0.81–4.52)

0.136

  1. Values in parentheses are 95% CI
  2. aLogistic regression with liver intervention as dependent variable
  3. bStage at initial diagnosis
  4. cIncluding rectal cancer
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BMC Cancer

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