Skip to main content

Table 4 Univariate and multivariate logistic regression analysis of patient and tumour factors associated with the probability of undergoing a liver intervention for CRCLM

From: Colorectal cancer liver metastases – a population-based study on incidence, management and survival

  Univariate analysisa Multivariate analysisa
Odds ratio (95% CI) P Odds ratio (95% CI) P
Patient factors
Age (years)
  > 68 1.00 (reference)   1.00 (reference)  
  ≤ 68 2.93 (1.63–5.24) <0.001 2.71 (1.29–5.69) 0.009
Sex
 Female 1.00 (reference)   1.00 (reference)  
 Male 1.52 (0.86–2.69) 0.146 0.94 (0.45–1.98) 0.879
Tumour factors
Tumour stageb
 T1 or T2 1.00 (reference)   1.00 (reference)  
 T3 or T4 0.31 (0.10–0.97) 0.045 0.16 (0.03–0.87) 0.035
Nodal stageb
 N0 1.00 (reference)   1.00 (reference)  
 N1 or N2 0.31 (0.16–0.62) 0.001 0.72 (0.31–1.67) 0.440
Time of detection
 Metachronous 1.00 (reference)   1.00 (reference)  
 Synchronous 0.41 (0.24–0.72) 0.002 1.20 (0.57–2.55) 0.626
No of liver metastases
 1–2 1.00 (reference)   1.00 (reference)  
 3–4 0.70 (0.32–1.56) 0.387 0.90 (0.33–2.46) 0.844
 ≥ 5 0.06 (0.02–0.14) <0.001 0.07 (0.03–0.19) <0.001
Tumour origin
 Right-sided 1.00 (reference)   1.00 (reference)  
 Left-sidedc 2.67 (1.31–5.44) 0.007 1.92 (0.81–4.52) 0.136
  1. Values in parentheses are 95% CI
  2. aLogistic regression with liver intervention as dependent variable
  3. bStage at initial diagnosis
  4. cIncluding rectal cancer