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Table 1 Demographics and clinical factors of patients and controls. Numbers in parentheses represent percent, unless otherwise noted. Disease-free controls (N = 31) were matched with the adenoma cases, and 50 controls were matched with patients with CRC

From: A quantitative multimodal metabolomic assay for colorectal cancer

  Subgroup Control Adenoma Stage I Stage II Stage III Stage IVa
N   31 + 9 + 41 31 8 8 8 38
Age, mean (SD)   60.5 (6.7) 59.5 (5.9) 76.9 (6.1) 67.3 (9.8) 62.8 (14.8) 60.5 (9.9)
Gender Male 58 (72) 21(68) 5 (63) 7(88) 4 (50) 30 (79)
Female 23 (28) 10 (32) 3 (37) 1 (11.2) 4 (50) 8 (11)
Primary Site Colon 2 3 5
Rectum 5 4 3
Unknown 1 1 0
Differentiation Poor 0 1 2 3
Moderate 4 5 4 26
Well 2 0 2 0
Unspecified 2 2 0 7 (+2 mucinous)
Staging T T1 1 3
T2 5 2
T3 7 1
T4 0 0
Unspecified 2 1 2  
Staging N N1 4 (N1a = 2) (N1b = 2) 8
N2 2 (N2a = 1) (N2b = 1) 8
Unspecified 2 22
Tumor dimension (cm) Largest dimension, mean (SD) 2.67 (1.50) 3.51 (1.99) 2.7 (2.09) 2.50 (1.49)
Min-Max    0.5–5 2.5–6 2.8–5.5 0.9–5.1
Pre-sampling Chemotherapy   1 (13) 3 (38) 4 (50) 17 (45)