Table 1 Demographics and clinical factors of patients and controls. Numbers in parentheses represent percent, unless otherwise noted. Disease-free controls (N = 31) were matched with the adenoma cases, and 50 controls were matched with patients with CRC

N

31 + 9 + 41

31

8

8

8

38

Age, mean (SD)

60.5 (6.7)

59.5 (5.9)

76.9 (6.1)

67.3 (9.8)

62.8 (14.8)

60.5 (9.9)

Gender

Male

58 (72)

21(68)

5 (63)

7(88)

4 (50)

30 (79)

Female

23 (28)

10 (32)

3 (37)

1 (11.2)

4 (50)

8 (11)

Primary Site

Colon

–

–

2

3

5

–

Rectum

–

–

5

4

3

–

Unknown

–

–

1

1

0

–

Differentiation

Poor

–

–

0

1

2

3

Moderate

–

–

4

5

4

26

Well

–

–

2

0

2

0

Unspecified

–

–

2

2

0

7 (+2 mucinous)

Staging T

T1

–

–

1

–

3

–

T2

–

–

5

–

2

–

T3

–

–

–

7

1

–

T4

–

–

–

0

0

–

Unspecified

–

–

2

1

2

Staging N

N1

–

–

–

–

4 (N1a = 2) (N1b = 2)

8

N2

–

–

–

–

2 (N2a = 1) (N2b = 1)

8

Unspecified

–

–

–

–

2

22

Tumor dimension (cm)

Largest dimension, mean (SD)

–

–

2.67 (1.50)

3.51 (1.99)

2.7 (2.09)

2.50 (1.49)

Min-Max

0.5–5

2.5–6

2.8–5.5

0.9–5.1

Pre-sampling Chemotherapy

–

–

1 (13)

3 (38)

4 (50)

17 (45)