Table 4 Multivariate analyses for disease-specific and overall survival
From: The prognostic value of TP53 mutations in hypopharyngeal squamous cell carcinoma
Variables | Overall (n = 57) | Stage III/IV (n = 52) | |||||||
|---|---|---|---|---|---|---|---|---|---|
DSS | OS | DSS | OS | ||||||
HR [95% CI] | P value | HR [95% CI] | P value | HR [95% CI] | P value | HR [95% CI] | P value | ||
TP53 | Wild-type vs. Mutation | 4.96 [1.08–22.8] | 0.04 | 4.75 [1.35–16.7] | 0.02 | 7.72 [0.98–60.7] | 0.05 | 5.51 [1.24–24.5] | 0.03 |
No. of metastatic LNs | ≤3 vs. ≥4 | 3.00 [1.12–8.04] | 0.03 | 2.89 [1.22–6.86] | 0.02 | 3.07 [1.13–8.35] | 0.03 | 2.89 [1.20–6.94] | 0.02 |
ENE | Absence vs. Presence | 1.85 [0.70–4.86] | 0.21 | 1.39 [0.59–3.27] | 0.45 | 1.81 [0.68–4.80] | 0.23 | 1.36 [0.58–3.21] | 0.48 |