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Table 3 Logistic Analysis of FISH Marker Combinations by Risk Category

From: Identification of fluorescence in situ hybridization assay markers for prediction of disease progression in prostate cancer patients on active surveillance

FISH Parameter Combination

Lower Risk

Intermediate Risk

Higher Risk

n Cases

n Controls

Odds Ratio

p Value

n Cases

n Controls

Odds Ratio

p Value

n Cases

n Controls

Odds Ratio

p Value

MYC Gain & FGFR1 Gain & PTEN Homozygous

29

25

6.017

0.0033

16

13

7.333

0.0192

13

11

3.143

0.2483

MYC Gain & PTEN Homozygous & NMYC Gain

29

25

6.017

0.0033

17

12

11.998

0.0082

15

9

2.000

0.4691

MYC Gain & PTEN Homozygous & NMYC Gain & FGFR1 Gain

28

26

4.886

0.0074

16

13

16.500

0.0035

11

13

6.250

0.1247

MYC Gain & PTEN Homozygous & ETV1 Split

29

25

6.017

0.0033

15

14

10.083

0.0082

14

10

4.000

0.1657

MYC Gain & PTEN Homozygous & NMYC Gain & 2 Edel

29

25

6.017

0.0033

18

11

8.999

0.0179

15

9

2.000

0.4691

MYC Gain & PTEN Homozygous & NMYC Gain & ETV1 Split

29

25

6.017

0.0033

17

12

11.998

0.0082

16

8

2.600

0.3253

MYC Gain & PTEN Homozygous & NMYC Gain & FGFR1 Gain & 2 Edel

29

25

6.017

0.0033

19

10

6.857

0.0369

15

9

2.000

0.4691