Preoperative serum immunoglobulin G and A antibodies to Porphyromonas gingivalis are potential serum biomarkers for the diagnosis and prognosis of esophageal squamous cell carcinoma

Table 1 Associations between serum IgG and IgA antibodies for P. gingivalis with clinicopathological features of ESCC

Variables		IgG Titer (EU)	P	IgA Titer (EU)	P
Age (n(%))	≤ 60(26(32.5%)	132.15 ± 62.13	0.46	31.54 ± 25.93	0.52
Age (n(%))	> 60(54(67.5%))	121.07 ± 62.65	0.46	38.23 ± 49.45	0.52
Gender (n(%))	Male(55(68.8%))	127.80 ± 62.18	0.51	37.52 ± 48.10	0.65
Gender (n(%))	Female(25(31.2%))	116.77 ± 63.30	0.51	32.84 ± 30.22	0.65
Tobacco use (n(%))	No(43(%))	122.62 ± 58.81	0.75	34.52 ± 30.12	0.73
Tobacco use (n(%))	Yes(37(%))	127.05 ± 66.87	0.75	37.84 ± 55.00	0.73
Alcohol use (n(%))	No(74(%))	125.57 ± 63.66	0.65	61.30 ± 74.42	0.60
Alcohol use (n(%))	Yes(6(%))	113.47 ± 44.82	0.65	54.28 ± 25.41	0.60
Differentiation grade (n(%))	Well(17(21.2%))	166.72 ± 71.77	0.15	36.47 ± 36.07	0.83
	Moderately(47(58.8%))	105.27 ± 45.26		35.12 ± 49.55
	Poorly(15(18.8))	140.28 ± 72.94		40.17 ± 29.95
T stage (n(%))	T1 + T2(17(21.5%))	121.72 ± 48.57	0.80	27.17 ± 20.14	0.33
T stage (n(%))	T3 + T4(62(78.5%))	126.08 ± 66.19	0.80	38.89 ± 47.61	0.33
Lymph node metastasis (n(%))	No(44(56.4%))	115.07 ± 57.03	0.19	42.94 ± 57.45	0.27
Lymph node metastasis (n(%))	Yes(34(43.6%))	134.05 ± 66.21	0.19	31.97 ± 28.31	0.27
TNM stage (n(%))	I–II(51(63.8%))	130.18 ± 62.58	0.34	31.77 ± 27.59	0.21
TNM stage (n(%))	III–IV(28(36.2%))	115.95 ± 62.60	0.34	44.73 ± 62.51	0.21

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