Table 2 Procedures of HR or TACE groups
Study | Â | TACE | Â | HR |
|---|---|---|---|---|
| Â | Duration and interval | Chemotherapeutic agents | Embolic agents | Methods and procedure |
Fan 2001 [20] | Median 2 times (ranged 1-4) | 5-fluorouracil (5-Fu) 1000Â mg, mitomycin (MMC) 12 to20 mg, cisplatin or carborplatinum 80Â mg | Lipiodol 20Â ml | En-bloc resection, partial hepatectomy or hemihepatectomy Thrombectomy |
Fan 2003 [19] | Median 2-3 times (ranged 1-7) | 5-fluorouracil (5-Fu) 1000-1500Â mg, cisplatin 80-100Â mg, mitomycin (MMC) 8 to20 mg or doxorubicin 80Â mg | Lipiodol 2-20Â ml | En-bloc resection, partial hepatectomy or hemihepatectomy Thrombectomy |
Cheng 2005 [18] | NA | Cisplatin, doxorubicin and mitomycin | Lipiodol | En-bloc resection, partial hepatectomy or hemihepatectomy Thrombectomy |
Fan 2005 [21] | Ranged 1-7 times | 5-fluorouracil (5-Fu) 1000-1500Â mg, cisplatin 80-100Â mg, mitomycin (MMC) 8-20Â mg or epiadriamycin 40-60Â mg | Lipiodol 5-20Â ml | En-bloc resection, partial hepatectomy or hemihepatectomy Thrombectomy |
Zhou 2011 [25] | Every 1-2Â months for 2-5Â cycles. | 5-fluorouracil (500Â mg /m2) and Adriamycin (30Â mg/m2) | Gelatin sponge particles (1Â mm3) | Hepatectomy plus thrombectomy |
Peng 2012 [12] | Mean of 2.1 (ranged 1-5) | Carboplatin 300Â mg, epirubicin 50Â mg and mitomycin C 8Â mg | Gelatin sponge particles (1 to 2Â mm in diameter) Lipiodol 5Â mL | Hepatectomy plus thrombectomy |
Liu PH 2014 [22] | NA | Adriamycin 20–30 mg | Lipiodol 5-10 ml Gelfoam (2–3-mm strips) | En-bloc resection, partial hepatectomy or hemihepatectomy Thrombectomy |
Liu K 2014 [17] | NA | Cisplatin 50-100Â mg and epirubicin 20-40Â mg | Lipiodol 5-20Â ml | En-bloc resection, partial hepatectomy or hemihepatectomy Thrombectomy |
Ye 2014 [24] | 1Â month intervals (ranged 1-7) | Doxorubicin 30-50Â mg and cisplatinum 50-100Â mg | Lipiodol 10-20Â ml and gelfoam particles | En-bloc resection, partial hepatectomy or hemihepatectomy Thrombectomy |
Lee 2016 [13] | Every 4Â weeks | Doxorubicin 50Â mg | Lipiodol | Hepatectomy plus thrombectomy |
Zheng 2016 [1] | Mean of 2.9 (ranged 1–7) | NA | Gelatin sponge | Hepatectomy plus thrombectomy |
Wang 2016 [11] | Intervals of 6 to 8Â weeks | Doxorubicin hydrochloride 20-60Â mg, and cisplatin 5Â mg | Lipiodol 5-30Â ml and gelfoam fragments | En-bloc resection, partial hepatectomy or hemihepatectomy Thrombectomy |