From: High neutrophil-to-lymphocyte ratios confer poor prognoses in patients with small cell lung cancer
Variables | NLR ≤ 4.55 | NLR > 4.55 | p value | ||
---|---|---|---|---|---|
n | n | ||||
Age (years, ± SD) | 57.61 ± 10.63 | 107 | 60.81 ± 9.70 | 32 | 0.129 |
Gender (male/female) | 81/26 | 107 | 26/6 | 32 | 0.513 |
Stage (LD/ED) | 50/57 | 107 | 6/26 | 32 | 0.005** |
Metastasis (yes/no) | 80/27 | 107 | 28/4 | 32 | 0.129 |
Brain metastasis (yes/no) | 7/100 | 107 | 2/30 | 32 | 1.000 |
Bone metastasis (yes/no) | 9/98 | 107 | 6/26 | 32 | 0.111 |
Liver metastasis (yes/no) | 11/96 | 107 | 9/23 | 32 | 0.020* |
Adrenal metastasis (yes/no) | 10/97 | 107 | 4/28 | 32 | 0.738 |
Pleural metastasis (yes/no) | 7/100 | 107 | 5/27 | 32 | 0.147 |
Lymph node metastasis (yes/no) | 72/35 | 107 | 27/5 | 32 | 0.061 |
Mediastinal metastasis (yes/no) | 3/104 | 107 | 1/31 | 32 | 1.000 |
Smoking (never/ever) | 32/75 | 107 | 7/25 | 32 | 0.375 |
Smoking amount (BI) | 660 (380–970) | 73 | 860 (600–1200) | 25 | 0.031* |
Family cancer history (yes/no) | 19/48 | 67 | 8/12 | 20 | 0.323 |
Exposure to cooking oil fume (never/ever) | 32/31 | 63 | 7/12 | 19 | 0.286 |
Operation (yes/no) | 12/95 | 107 | 2/30 | 32 | 0.413 |
Radiotherapy (yes/no) | 52/55 | 107 | 9/23 | 32 | 0.041* |
Chemotherapy (yes/no) | 96/11 | 107 | 24/8 | 32 | 0.043* |
PLR | 115 (89–165) | 107 | 221 (175–324) | 32 | 0.000*** |
RBC (1012/L) | 4.49 (4.17–4.88) | 107 | 4.18 (3.47–4.47) | 32 | 0.002** |
Hb (g/L) | 135 (124–146) | 107 | 120 (106–134) | 32 | 0.001** |
MCV (fL) | 91.4 (87.8–94.1) | 107 | 92.2 (87.6–93.8) | 32 | 0.906 |
PLT (109/L) | 181 (138–228) | 107 | 206 (169–289) | 32 | 0.035* |
WBC (109/L) | 6.13 (5.07–7.23) | 107 | 7.34 (6.34–9.75) | 32 | 0.001** |
Neutrophil (109/L) | 4.08 (3.00–4.98) | 107 | 5.62 (4.98–7.58) | 32 | 0.000*** |
Lymphocyte (109/L) | 1.46 (1.22–1.82) | 107 | 0.96 (0.71–1.10) | 32 | 0.000*** |
Alb (g/L) | 41.2 (38.6–43.6) | 104 | 37.1 (33.0–40.2) | 32 | 0.000*** |
LDH (U/L) | 193 (175–238) | 102 | 264 (205–360) | 31 | 0.001** |
ALP (U/L) | 79 (65–95) | 104 | 82 (59–114) | 32 | 0.595 |
CHO (mmol/L) | 4.46 (4.06–4.90) | 102 | 3.87 (3.30–4.47) | 31 | 0.000*** |
TG (mmol/L) | 1.22 (0.88–1.45) | 102 | 1.06 (0.87–1.46) | 31 | 0.661 |
HDL-C (mmol/L) | 1.25 (1.08–1.54) | 102 | 1.09 (0.94–1.34) | 31 | 0.007** |
LDL-C (mmol/L) | 2.63 (2.27–3.00) | 102 | 2.23 (1.63–2.72) | 31 | 0.001** |
CR (μmol/L) | 76.1 (65.3–87.9) | 104 | 67.6 (55.4–83.7) | 32 | 0.082 |
CEA (ng/ml) | 3.71 (1.80–9.13) | 85 | 3.66 (2.04–10.25) | 29 | 0.747 |
CYFRA21-1 (ng/ml) | 3.10 (2.27–4.84) | 75 | 4.76 (2.78–7.43) | 26 | 0.017* |
NSE (ng/ml) | 38.85 (22.86–97.62) | 86 | 71.29 (37.66–113.23) | 26 | 0.034* |