Skip to main content

Advertisement

Table 3 Questionnaire and feeding tube results for CB-EST

From: Feasibility and acceptability of combining cognitive behavioural therapy techniques with swallowing therapy in head and neck cancer dysphagia

Measure Pre-CB-EST Post CB-EST 3 months ANOVA, Effect size (ES) Pre to post [95% CI] Pre to 3 m [95% CI] Post to 3 m [95% CI]
MDADI n = 25 (100%) n = 23 (92%) n = 24 (96%)     
  53.1 (15.1) 61.2 (15.6) 61.8 (16.0) p = 0.002 (2,42) F = 8.8 ES = 0.29* p = 0.03 [0.7–15.5] p = 0.003 [2.6–14.6] p = 1.0 [3.6–4.7]
QLQ-C30 n = 25 (100%) n = 22 (88%) n = 19 (76%)     
Physical 63.7 (21.8) 74.1 (21.9) 74.4 (21.8) p = 0.006 (2,34) F = 5.9 ES = 0.26 p = 0.05 [0.1–28.8] p = 0.03 [0.7–20.8] p = 1.0 [−8.1–7.2]
Role 48.1(38.3) 61.1(34.7) 72.2(34.3) p = 0.03 (1,20) F = 4.8 ES = 0.22* p = 0.5 [10.9–36.8] p = 0.06 [1.2–49.4] p = 0.01 [2.3–19.9]
Emotional 67.6 (31.0) 75.9 (31.7) 75.4 (24.8) p = 0.15 (1,17) F = 2.3 ES = 0.11 p = 0.06 [0.4–17.1] p = 0.4 [5.9–21.7] p = 1.0 [11.9–12.9]
Cognitive 70.4 (34.6) 75.9 (34.9) 87.0 (19.4) p = 0.06 (2,21) F = 3.8 ES = 0.18* p = 0.2 [2.4–13.5] p = 0.1 [2.6–35.9] p = 0.4 [7.8–30.0]
Social 44.4 (37.0) 65.7 (36.8) 62.9 (36.8) p = 0.004 (2,34) F = 6.5 ES = 0.28 p = 0.03 [1.1–41.4] p = 0.01 [3.8–33.2] p = 1.0 [12.9–18.5]
Symptoms
 Fatigue 40.7(24.9) 33.9 (26.8) 26.5(25.6) p = 0.02 (2,34) F = 4.2 ES = 0.2 p = 0.79 [8.8–22.4] p = 0.02 [1.4–27.0] p = 0.2 [2.7–17.5]
 Nausea 12.9 (25.9) 5.5 (9.9) 8.3 (17.4) p = 0.2 (2,34) F = 1.6 ES = 0.1 p = 0.41 [5.1–19.9] p = 0.86 [−6.5–15.8] p = 1.0 [−11.7–6.2]
 Pain 31.5 (32.3) 29.9 (34.8) 26.8 (30.3) p = 0.71 (2,34) F = 0.3 ES = 0.02 p = 1.0 [14.4–25.5] p = 1.0 [18.5–27.7] p = 1.0 [12.7–14.5]
QLQ-H&N35 n = 25 (100%) n = 22 (88%) n = 22 (88%)     
Oral pain 32.2 (19.8) 23.3 (22.7) 27.1 (21.9) p = 0.29 (2,38) F = 1.3, ES = 0.06 p = 0.29 [−4.0–19.8] p = 1.0 [−9.8–17.5] p = 1.0 [−17.3–9.8]
Swallow 45.8 (31.2) 35.0 (26.0) 28.3 (18.2) p = 0.006 (2,38) F = 5.9, ES = 0.24 p = 0.2 [−4.1–25.7] p = 0.01 [3.8–31.1] p = 0.46 [−5.1–18.4]
Senses 45.5 (29.4) 32.5 (21.2) 22.5 (26.6) p < 0.0001 (2,38) F = 10.7, ES = 0.36 p = 0.09 [−1.8–21.2] p = 0.003 [6.3–33.7] p = 0.02 [1.4–18.6]
Speech 40.8 (35.6) 28.3 (35.9) 20.8 (22.8) p = 0.01 (2,38) F = 5.1, ES = 0.21 p = 0.02 [1.1–28.9] p = 0.04 [0.8–39.2] p = 0.89 [−10.9–25.8]
Social eating 58.7 (37.8) 36.1(27.0) 38.3 (35.1) p = 0.006 (2,38) F = 5.9, ES = 0.24 p = 0.03 [1.2–44.1] p = 0.05 [−0.5–41.4] p = 1.0 [−16.0–11.6]
Social context 31.0 (25.9) 16.3 (22.7) 15.7 (17.5) p = 0.001 (2,38) F = 9.0, ES = 0.32 p = 0.01 [2.7–26.6] p = 0.004 [4.5–26.1] p = 1.0 [−8.6–9.9]
Sexuality 53.3 (44.1) 48.3 (46.2) 35.0 (46.1) p = 0.12 (2,38) F = 0.23, ES = 0.11 p = 1.0 [−21.8–31.8] p = 0.06 [−0.7–37.4] p = 0.47 [−10.3–37.0]
CFS n = 25 (100%) n = 24 (96%) n = 22 (88%)     
  20.3 (5.0) 16.2 (6.8) 15.9 (5.9) p = 0.002 (2,42) F = 7.3, ES = 0.39 p = 0.04 [0.1–8.1] p = 0.04 [0.1–8.1] p = 1.0 [2.5–2.9]
WASA n = 25 (100%) n = 23 (92%) n = 22 (88%)     
  20.0 (9.2) 13.9(11.6) 16.9 (22.5) p = 0.34(2,40) F = 1.1, ES = 0.05* p = 0.07 [0.5–12.7] p = 1.0 [9.2–15.3] p = 1.0 [9.2–15.3]
HADS n = 25 (100%) n = 23 (92%) n = 22 (88%)     
Anxiety 6.9 (4.9) 6.6 (5.9) 5.9 (4.1) p = 0.54 (2,38) F = 0.6, ES = 0.03 p = 1.0 [−1.8–2.7] p = 0.8 [−1.4–3.3] p = 1.0 [−1.6–2.6]
Depression 6.0 (3.4) 5.6 (4.1) 4.9(4.1) p = 0.49 (2,38) F = 0.7, ES = 0.37 p = 1.0 [−2.0–2.8] p = 0.78 [−1.4–3.6] p = 1.0 [−1.6–3.0]
Total 12.8 (7.1) 12.0 (9.6) 10.8 (3.4) p = 0.38 (2,38) F = 1.0, ES = 0.05 p = 1.0 [−2.9–4.6] p = 0.58 [−1.9–6.0] p = 1.0 [−2.7–5.1]
PSS Diet n = 25 (100%) n = 25 (100%) n = 24 (96%)     
  39.2 (19.9) 55.0 (14.4) 61.3 (18.5) p < 0.0001 (2,46) F = 15.0, ES = 0.4* p = 0.002 [5.3–26.4] p = 0.001 [8.3–35.8] p = 0.8 [0.4–12.9]
Feeding tube n = 30 n = 25 n = 25     
None 14 (56%) 22 (88%) 22 (88%)     
Nasogastric 9 (30%) 1 (4%) 0     
Gastrostomy 7 (24%) 2 (8%) 3 (12%)     
  1. QLQ-C30, MDADI, CFS, WASA, HADS, PSS Diet higher score is better patient reported outcome. QLQ-H&N35 and HADS lower score indicates better patient reported outcome *sphercity violated for repeated measures ANOVA and adjusted using epsilon correction