Table 2 Baseline serum cytokines in Cohort 1 (hepatic arterial infusion chemotherapy-treated patients)
Cytokines (pg/mL, mean ± SE) | CR/PR group | SD/PD group | P-valuea |
|---|---|---|---|
EGF | 20.8 ± 3.8 | 21.6 ± 3.0 | 0.882 |
FGF | 2.84 ± 1.63 | 8.40 ± 2.53 | 0.134 |
HGF | 523.9 ± 50.3 | 739.8 ± 71.6 | 0.043 |
IFN-γ | 0.109 ± 0.064 | 1.343 ± 0.699 | 0.203 |
IL-10 | 0.813 ± 0.169 | 1.239 ± 0.219 | 0.193 |
IL-12 (p70) | 8.41 ± 1.17 | 10.77 ± 1.05 | 0.164 |
IL-2 | 0.297 ± 0.092 | 1.118 ± 0.568 | 0.299 |
IL-4 | 0.586 ± 0.170 | 1.213 ± 0.197 | 0.038 |
IL-5 | 17.3 ± 5.5 | 15.6 ± 2.0 | 0.718 |
IL-6 | 10.90 ± 3.94 | 9.05 ± 1.65 | 0.614 |
IL-8/CXCL8 | 61.3 ± 37.1 | 18.7 ± 2.7 | 0.119 |
CXCL10 | 358.3 ± 41.1 | 359.1 ± 30.3 | 0.988 |
CXCL9 | 176.6 ± 14.0 | 205.8 ± 30.6 | 0.502 |
PDGF-BB | 152.5 ± 20.9 | 193.6 ± 24.3 | 0.265 |
SCF | 14.1 ± 1.3 | 16.4 ± 1.0 | 0.189 |
SDF-1 | 60.3 ± 26.3 | 13.1 ± 5.0 | 0.022 |
TGF-β | 5.17 ± 3.42 | 1.64 ± 0.71 | 0.188 |
TGF-α | 34.0 ± 23.8 | 14.2 ± 6.3 | 0.307 |
TNF-α | 1.23 ± 0.31 | 1.87 ± 0.30 | 0.184 |
VEGF-A | 65.1 ± 9.4 | 83.6 ± 6.9 | 0.116 |