Table 2 Background information about drugs included in the analysisa
Generic drug name | Product name | FDA approved indications | Selected presentation | Country coverage | Unit price is price of: | |
|---|---|---|---|---|---|---|
# | Missing data | |||||
Abiraterone acetate | Zytiga | Metastatic castration-resistant prostate cancer | 120 tablets 250 mg | 7 | PAK, MYS, LBN | 1 Tab |
Bevacizumab | Avastin | NSCLC Metastatic Colorectal cancer, Glioblastoma Metastatic Renal cell carcinoma Metastatic Her2 negative breast cancer Metastatic cervical cancer. | One 4 ml vial containing 25 mg/mL concentrate for solution for infusion. | 6 | MYS, SAU, OMN, LBN | 4 ml vial |
Bortemozib | Velcade | One vial containing 3·5 mg powder for solution for injection. | 7 | EGY, PAK, SAU | 1 vial | |
Cabazitaxel | JEVTANA® | Metastatic hormone refractory prostate cancer | One vial containing 60 mg concentrate and solvent for solution for infusion. | 4 | EGY, PAK,THA, SAU, BHR,TWN, | 1 vial |
Cetuximab | Erbitux | K-ras wild-type, EGFR-expressing metastatic colorectal cancer. Recurrent/metastatic head and neck cancer | One vial containing 5 mg/mL solution for infusion. | 4 | ARE, EGY, PAK, SAU,OMN, BHR | 1 vial |
Denosumab | Prolia | Unresectable giant cell tumor of bone in adults and skeletally mature adolescents | One pre-filled syringe containing 60 mg solution for injection | 6 | PAK, MYS, SAU, BHR | One pre-filled syringe |
Erlotinib HCl | Tarceva | Non-small cell lung cancer. Pancreatic cancer. | 30 film-coated tablets 150 mg | 7 | MYS, SAU, LBN | 1 film-coated Tab |
Everolimus | Afinitor | Subependymal giant cell astrocytoma. HER2-negative breast cancer. Progressive neuroendocrine Tumors of Pancreatic origin. Advanced renal cell carcinoma. | 30 tablets 10 mg | 8 | PAK, MYS, | 1 Tab |
Gefitinib | Iressa | Non-small cell lung cancer | 30 film-coated tablets 250 mg | 7 | EGY, SAU,PAK | 1 film coated Tab |
Gemcitabine | Gemita (Atco) | Ovarian cancer Breast cancer. NSLCLC Pancreatic cancer | 1 vial containing 1 g powder for solution for infusion. | 9 | SAU | 1 vial |
Imatinib Mesylate | Glivec (Novertis) | Dermatofibrosarcoma protuberans. Gastrointestinal stromal tumor. Myelodysplastic/myeloproliferative neoplasms. | 60 film-coated tablets 100 mg | 9 | BHR | 1 film coated Tab |
Interferon Alpha - 2B | Interon A (Schering Plough | AIDS related Kaposi Sarcoma. Hairy cell leukemia. Melanoma. NHL | One multi-dose pen containing 3 million IU/0·5 mL solution for injection. | 6 | THA, EGY, MYS,OMN | One multi-dose pen |
Lapatinib ditosylate | Tykerb FC | HER2 positive breast cancer, | 70 film-coated tablets 250 mg | 7 | MYS, BHR, TWN | 1 film coated Tab |
Nilotinib | Tasigna | CML | 112 capsules 150 mg | 8 | PAK, MYS | 1 Cap |
112 capsules 200 mg | 6 | THA,LBN, OMN, BHR | 1 Cap | |||
Paclitaxel Albumin | Intaxel 30 mg/5 ml inj | NSCLC Breast cancer pancreatic cancer | One vial containing 5 mg/ml powder for suspension for infusion. | 6 | ARE, EGY, SAU, BHR | 1 Vial |
Panitumumab | Vectibix 400 mg/20 ml IV | Colorectal Cancer | One vial containing 20 mg/ml concentrate for solution for infusion | 6 | THA, PAK, MYS, TWN | 1 Vial |
Pazopanib | votrient | 30 film-coated tablets 200 mg | 8 | PAK, MYS | 1 film coated Tab | |
Pemetrexed Disodium Heptahydrate | Alimta (Eli Lilly) | non-squamous NSCLC Malignant pleural mesothelioma | One vial containing 20 mg/ml solution for injection. | 9 | OMN | 1 Vial |
Sorafenib | Nexavar (Bayer Schering) | Liver cancer Kidney cancer Thyroid cancer | 60 film-coated tablets 200 mg. | 5 | THA, MYS, OMN, BHR,LBN | 1 film coated Tab |
Sunitinib malate | SUTENT (Pfizer) | Kidney cancer Gastointestinal stromal tumour Pancreatic Neuroendocrine tumours | 28 capsules 12.5 mg | 7 | OMN, LBN, BHR | 1 Cap |
28 capsules 25 mg | 4 | THA, LBN, MYS, OMN, BHR, TWN, | 1 Cap | |||
28 capsules 50 mg | 6 | THA, LBN, MYS, OMN, | 1 Cap | |||
Trastuzumab | Herceptin (Roche) | Her2 over expressing breast cancer Her2 over expressive Gastric or Gastroesophageal junction Adenocarcinoma | One vial containing 440 mg powder for concentrate for solution for infusion | 4 | THA, LBN, MYS, SAU,OMN, BHR | 1 Vial |
One vial containing 150 mg powder for concentrate for solution for infusion | 4 | ARE, EGYP, PAK, LBN, MYS, TWN, | 1 Vial | |||
Zolendronic acid | ZOLDIC | Multiple Myeloma | One vial containing 4 mg/5 ml concentrate for solution for infusion | 4 | ARE, LBN, MYS, OMN, BHR, TWN | 1 Vial |