Table 4 Hazard ratio (HR) of incident colorectal cancer associated with Homeostasis Model Assessment for Insulin Resistance (HOMA2-IR) for men and women in the Malmö Diet and Cancer Study cardiovascular cohort
From: High blood glucose levels are associated with higher risk of colon cancer in men: a cohort study
Unadjusted model | Full model | |||||
|---|---|---|---|---|---|---|
Quartiles of HOMA2-IR | Min-max (mIU/l) | Cases/person-years | HR | 95% CI | HR | 95% CI |
Men (n = 1824) | ||||||
1 | 0.35–0.63 | 6/3938 | 1.00 | 1.00 | ||
2 | 0.64–0.90 | 9/7615 | 0.66 | 0.30, 1.47 | 0.64 | 0.29, 1.44 |
3 | 0.91–1.28 | 19/8618 | 1.35 | 0.69, 2.63 | 1.29 | 0.65, 2.56 |
4 | 1.29–6.85 | 30/9434 | 1.80 | 0.95, 3.41 | 1.62 | 0.81, 3.25 |
p for trend | 0.042 | 0.132 | ||||
Women (n = 2627) | ||||||
1 | 0.34–0.51 | 17/9764 | 1.00 | 1.00 | ||
2 | 0.52–0.77 | 21/12496 | 1.26 | 0.67, 2.37 | 1.11 | 0.59, 2.09 |
3 | 0.78–1.06 | 18/11908 | 1.15 | 0.60, 2.18 | 0.97 | 0.50, 1.89 |
4 | 1.07–7.30 | 15/10309 | 0.97 | 0.49, 1.89 | 0.77 | 0.37, 1.59 |
p for trend | 0.760 | 0.779 | ||||