The preventive effect of sensorimotor- and vibration exercises on the onset of Oxaliplatin- or vinca-alkaloid induced peripheral neuropathies - STOP

Table 1 Flow-chart of assessments

		Baseline T0	T1	Tp	T2	Ti	Status measurement
Time points		Prior to first cycle of therapy	After 3 months	After medical therapy	3 month follow-up	Incidence CIPN	every 6 weeks
Intervention	Training	2 x per week throughout entire medical therapy			Patients offered to continue
Anamnesis I	Entity, stadium, pre-treatment, pre-diseases, allergies, planed therapy, neurological anamnesis, CIPN relevant medication, social anamnesis	X
Anamnesis II	Begin of CIPN Symptoms, reception of planed therapy. Amount of cycles, potential change of medication or therapy, CIPN relevant medication			X	X	X
Anamnesis III	Reception of CIPN relevant medication, therapy of CIPN			Only CG	Only CG	Only CG
Neurological assessment	Neuroelectrography (NCV, Amp)	X	X	X	X	X
	Neurological clinical tests battery	X	X	X	X	X	X
Performance status	Static and dynamic postural control	X	X	X	X	X
Questionnaires	Subjective reduction of symptoms (FACT/GOG-Ntx / EORTC CIPN 20) Quality of life (EORTC QLQ-C 30) Neuropathic pain (PainDETECT and VAS) Level of physical activity (FFKA)	X	X	X	X	X

CIPN Chemotherapy-induced peripheral neuropathy, CG control group, NCV nerve conduction velocity, Amp amplitude, VAS visual analogue scale

ISSN: 1471-2407