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Table 1 Definition of abnormal blood test results for the 28 included blood tests

From: Routine blood tests and probability of cancer in patients referred with non-specific serious symptoms: a cohort study

Blood test interval

Reference group

Definition of abnormal result

Inflammation

CRP

High

All

≥8.0 mg/l

ESR

High

Men under 50 years old

Men 50 years or older

Women under 50 years old

Women 50 years or older

≥ 15 mm/h

≥ 20 mm/h

≥ 20 mm/h

≥ 30 mm/h

Immunology

IgA

Low

All

< 0.8 g/l

 

High

Under 50 years old

50 years or older

> 3.90 g/l

> 4.90 g/l

IgG

Low

All men, and women 50 years or older

Women under 50 years old

< 6.1 g/l

< 6.9 g/l

 

High

All men, and women 50 years or older

Women under 50 years old

> 14.9 g/l l

> 15.7 g/l

IgM

Low

All men, and women 50 years or older

Women under 50 years old

< 0.39 g/l

< 0.55 g/l

 

High

All men, and women 50 years or older

Women under 50 years old

> 2.08 g/l

> 2.30 g/l

Haematology

White blood cell count

Low

All

< 3.5 × 109/l

High

All

> 10.0 × 109/l

Neutrophil count

Low

All

< 2.0 × 109/l

High

All

> 7.0 × 109/l

Eosinophil count

High

All

≥ 0.5 × 109/l

Basophil count

High

All

≥ 0.10 × 109/l

Metamyelocyte count

High

All

≥ 0.05 × 109/l

Monocyte count

Low

All

< 0.2 × 109/l

High

All

> 0.7 × 109/l

Lymphocyte count

Low

All

< 1.3 × 109/l

High

All

> 3.5 × 109/l

Platelet count

Low

Men

Women

< 145 × 109/l

< 165 × 109/l

High

Men

Women

> 350 × 109/l

> 400 × 109/l

Anaemia

   

Haemoglobin

Low

Men

Women

< 8.3 mmol/l

< 7.3 mmol/l

Liver and metabolism

Albumine

Low

Under 70 years old

70 years or older

< 36 g/l

< 34 g/l

Alkaline phosphatase

High

All

> 105 U/l

ALK

High

Men

Women

> 70 U/l

> 45 U/l

Bilirubin

High

All

> 25 μmol/l

Amylase

High

All

> 120 U/l

Calcium total

High

All

> 2.55 mmol/l

LDH

High

Under 70 years old

70 years or older

>205 U/l

>255 U/l

Uric acid

High

Men

Women under 50 years old

Women 50 years or older

>0.48 mmol/l

>0.35 mmol/l

>0.40 mmol/l

Tumour markers

M protein

High

All

≥ 2.0 g/l

sFLC ratio

Low

All

< 0.26

High

All

> 1.65

AFP

High

All

≥ 7 KU/l

PSA

High

Men under 60 years old

Men between 60 and 69 years old

Men 70 years or older

≥ 3.0 μg/l

≥ 4.0 μg/l

≥ 5.0 μg/l

hCG

High

Men

≥ 2 IU/l

CA-125

High

Women

≥ 35 kIU/l

  1. The blood tests were divided into intervals according to the reference range used at the Department of Clinical Chemistry at Silkeborg Regional Hospital
  2. Abbreviations: CRP C-reactive protein, ESR erythrocyte sedimentation rate, IgA immunoglobulin A, IgG immunoglobulin G, IgM immunoglobulin M, ALT alanine aminotransaminase, LDH lactate dehydrogenase. sFLC serum-free light chain κ/λ ratio, AFP alpha-fetoprotein, PSA prostate-specific antigen, hCG human chorionic gonadotropin, CA-125 cancer antigen 125