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Table 1 Comparisons of demographic and clinical characteristics between cases and controls and between invasive ductal carcinoma and ductal carcinoma in situ

From: Comparison of the association of mammographic density and clinical factors with ductal carcinoma in situ versus invasive ductal breast cancer in Korean women

Variables

All cases (n = 562)

Invasive Ductal carcinoma (n = 472)

Ductal carcinoma in situ (n = 90)

Control (n = 1088)

Pdifference*

Pdifference†

Age at mammogram, years, mean (SD)

48.7(7.5)

48.9(7.6)

48.1(7.1)

49.3(7.1)

<0.001

0.358

Premenopausal, N (%)

389 (69.2)

323 (68.4)

66 (73.3)

742 (65.6)

–

0.356

Body mass index, kg/m2, mean (SD)

22.9(2.9)

23.1(3.0)

21.8(2.4)

22.5(2.8)

0.002

<0.001

Age at menarche, years, mean (SD)

14.7(1.7)

14.6(1.7)

14.8(1.7)

14.9(1.6)

0.003

0.357

Number of live birth, mean (SD)

1.9(0.9)

1.9(0.9)

1.8(1.0)

2.0(1.0)

0.001

0.714

Ever-use of estrogen replacement, N (%)

40 (7.1)

36 (7.6)

4 (4.4)

107 (9.8)

0.066

0.489

Ever alcohol consumption, N (%)

271 (48.2)

223 (47.3)

48 (53.3)

413 (38.0)

<0.001

0.290

Ever smoking, N (%)

46 (8.2)

40 (8.5)

6 (6.7)

54 (5.0)

0.009

0.566

Doing physical exercise ≥3/week, N (%)

185 (32.9)

164 (34.8)

21 (23.3)

280 (25.8)

0.001

0.035

Doing physical exercise, ≥ 1/week, N (%)

299(53.2)

248(52.5)

51(56.7)

902(82.9)

<0.001

0.472

Previous benign breast disease, N (%)

155 (27.6)

127 (26.9)

28 (31.1)

71 (6.5)

<0.001

0.413

Breast cancer among first degree relatives, N (%)

56 (10.0)

49 (10.4)

7 (7.8)

42 (3.9)

<0.001

0.450

Tumor marker status, N (%)

      

Estrogen receptor (+)

444 (79.1)

373 (79.0)

71 (79.8)

  

0.873

Progesterone receptor (+)

401 (71.5)

334 (70.8)

67 (75.3)

  

0.387

Human epidermal growth factor receptor-2 (+)

134 (25.2)

103 (23.0)

31 (36.5)

  

0.009

Mammographic density measures

      

Total breast area, cm2, mean (SD)

101.9(37.2)

103.9(38.0)

91.3(31.1)

94.9(33.6)

<0.001

0.001

Dense area, cm2, mean (SD)

20.4(14.5)

20.7(14.8)

19.1(13.0)

17.0(12.6)

<0.001

0.355

Nondense area, cm2, mean (SD)

81.5(36.3)

83.2(36.6)

72.1(33.2)

78.0(33.5)

0.033

0.008

Percent density, %, mean (SD)

21.4(13.5)

21.1(13.2)

22.8(14.9)

18.8(12.2)

<0.001

0.287

  1. SD standard deviation, N number
  2. *P value for the difference between cases and matched controls was assessed by paired t test for continuous variables or Cochran-Mantel-Haenszel chi-square test for categorical variables
  3. †P value for the difference between the cases with invasive ductal carcinoma and the cases with ductal carcinoma in situ was assessed by student t test for continuous variables or Chi-square test for categorical variables
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BMC Cancer

ISSN: 1471-2407

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