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Table 1 Resistance of ovarian cancer cells to cisplatin after metformin treatment

From: Inhibition of the IGF signaling pathway reverses cisplatin resistance in ovarian cancer cells

Cells

Cisplatin IC50 (μg/mL)

Fractional inhibitory index

A2780

3.12 ± 0.048

 

CP70

  

 0 mM/metformin

29.16 ± 0.805

9.34

 0.01 mM/ metformin

26.43 ± 0.437

8.45

 0.1 mM/metformin

23.52 ± 0.432

7.53

 1 mM/metformin

19.26 ± 0.215*

6.17

 10 mM/ metformin

10.04 ± 0.327*

3.23

  1. *P < 0.05 compared with 0.01 mM metformin
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BMC Cancer

ISSN: 1471-2407

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