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Table 2 Odds Ratios, 95% CI, and p values for the association between serum selenium and prevalent ESD in the Tenwek ESD study

From: Cross sectional study of serum selenium concentration and esophageal squamous dysplasia in western Kenya

Scaled Serum Seleniuma

OR

95% CI

p value

 Crude Model

1.29

1.04–1.61

0.02

 Age and Sex Adjusted

1.30

1.04–1.63

0.02

 Fully Adjustedb

1.42

1.04–1.93

0.03

Selenium Quartile

Q1

Q2

Q3

Q4

 Mean Concentration (μg/L)

53

68

87

122

 Range (μg/L)

36-61

62-73

74-99

100-188

ESD Cases, N (%)

5 (12)

5 (12)

 

15 (36)

 

17 (40)

 

P for trend

 

Ref

OR

95% CI

OR

95% CI

OR

95% CI

 Crude Model

1

1.02

0.28–3.71

2.42

0.83–7.04

3.03

1.05–8.74

0.01

 Age and Sex Adjusted

1

1.02

0.28–3.72

2.25

0.76–6.66

2.95

1.02–8.55

0.02

 Fully Adjustedb

1

1. 13

0.29–4.37

2.71

0.84–8.69

3.87

1.06–14.19

0.02

  1. aSelenium scaled to ½ Interquartile range (20 μg/L)
  2. bAdjusted for age (years), sex, education, location (A, B, or C), family history of cancer, family history of esophageal cancer, tobacco (regular use), and alcohol (regular use)
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BMC Cancer

ISSN: 1471-2407

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