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Fig. 9 | BMC Cancer

Fig. 9

From: Decreased expression of the β2 integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice

Fig. 9

The impaired β2 expression on tumor cells correlates with the reduced recruitment of CD11b+Ly6G+, CD4+T lymphocytes and CD8+ T lymphocytes at late stages of C26 cells colonization of the liver. a The recruitment of CD11b+ and Ly6G+ (a), CD4+ T cells (b) and CD8+ T cells (c) to the liver was immuhistochemically analyzed 14 days after i.s. inoculation of C26 cells. The quantification of CD4+, CD8+, CD11b+ and Ly6G+ (Gr1+) cell numbers was carried out in 3 different sections per mice, and at least 5 mice per group were used per each experiment and each one was performed 3 times. Data are mean values ± SD from 10 different fields/100 mm2 liver tissue section. Changes were considered statistically significant at *p < 0.05 and at least 5 mice per group were used per each experiment and each one was performed 3 times

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