Fig. 1
From: CCL5-CCR5 interactions modulate metabolic events during tumor onset to promote tumorigenesis
MMTV-PyMT.CCR5−/− mice have delayed tumor onset and increased tumor free survival compared to MMTV-PyMT.CCR5+/+ mice. a, b MMTV-PyMT.CCR5+/+ and MMTV-PyMT.CCR5−/− mice were monitored daily for palpable tumors, using calipers. Tumor onset is defined as detection of a palpable tumor, volume ~20mm3. Tumor endpoint is defined as a palpable tumor with volume ~700mm3. Mice were euthanized when tumors reached this size. Each data point represents a single mouse. Means and SEM are identified as horizontal lines. c Tumor-free survival rate is the percentage of the mice in the colony that are tumor-free at each specified age. * * p < 0.01