Fig. 2

Intra-tumor molecular subtype heterogeneity (n = 12 tumors). a PCA score plot of the prospective study (points) and the heterogeneity set (points connected by lines for pieces from the same tumor) (Key: LumA = Luminal A (red colour dots), LumB = Luminal B (blue colour dots), HER2 = HER2-enriched (green colour dots), Basal = Basal-like (purple colour dots) and Normal = Normal breast-like (orange colour)). Intra-tumor pieces from each patient are connected through respective coloured lines as illustrated in the figure legend. b Predicted ER status, HER2 status, transcriptomic grade and molecular subtypes for all the tumor pieces (n = 43) are summarised in a table format. Two patient IDs are coloured in red fonts, are the ones which exhibited heterogeneous molecular subtypes or transcriptomic grades