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Table 1 Baseline characteristics of the study population

From: Serum albumin level as a potential marker for deciding chemotherapy or best supportive care in elderly, advanced non-small cell lung cancer patients with poor performance status

  Chemotherapy (N = 31) Best supportive care (N = 28) p-value
Age 78.0 [76.5–80.0] 80.5 [77.0–84.3] 0.118
Gender (male/female) 4 / 27 4 / 24 1.00
ECOG Performance Status (2/3/4) 18/12/1 8/15/5 0.0350
Smoking history 30 (96.8%) 22 (78.6%) 0.0870
Brinkman Index 1100 [780–1550] 800 [420–1395] 0.113
Comorbidities
 Emphysema (%) 26 (83.9%) 20 (71.4%) 0.348
 Interstitial pneumonia (%) 1 (3.2%) 1 (3.6%) 1.00
 Diabetes mellitus (%) 13 (41.9%) 1 (3.6%) 0.00100
Histology (Non-Squamous/Squamous) 6 / 25 6 / 22 1.00
Staging (IIB/IV) 5 / 26 2 / 26 0.428
Major diameter of the primary site 39.5 [27.5–65.0] 52.0 [40.5–74.0] 0.0740
Metastatic organ
 Brain (%) 6 (19.4%) 4 (14.3%) 0.734
 Bone (%) 10 (32.3%) 6 (21.4%) 0.393
 Liver (%) 3 (9.7%) 3 (10.7%) 1.00
 Adrenal gland (%) 4 (12.9%) 1 (3.6%) 0.356
Laboratory data
 White blood cell count 7800 [6450–9700] 7700 [6175–11,925] 0.802
 Neutrophil count 5336 [4502–6684] 5988 [4513–8929] 0.362
 Lymphocyte count 1396 [1148–1721] 1086 [848–1432] 0.0370
 Hemoglobin 12.4 [11.0–14.0] 12.0 [11.5–13.2] 0.885
 Albumin 3.60 [3.20–3.95] 3.30 [2.85–3.62] 0.0460
 Lactate dehydrogenase 214 [188–247] 247 [206–277] 0.141
 Calcium 9.20 [9.00–9.55] 9.00 [8.47–9.33] 0.093
 C-reactive protein 1.81 [0.66–3.92] 3.20 [0.57–7.59] 0.391
  1. Categorical data are presented as numbers (percentages) whereas continuous data are presented as medians (interquartile ranges). Fisher’s exact test was used to compare categorical data, and the Mann–Whitney U test was used to compare continuous data
  2. Abbreviations: ECOG Eastern Cooperative Oncology Group