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Table 3 Association of demographic and clinicopathologic profiles with IHC defined subtypes of BC in both Eritrean and Sudanese women

From: Immunohistochemistry defined subtypes of breast cancer in 678 Sudanese and Eritrean women; hospitals based case series

Demographic and tumour characteristics IHC defined breast cancer subtypes P value
Luminal A Luminal B HER2 enriched TNBC
n % n % n % n %
Age in years ≤50 131 37.1% 35 9.9% 53 15.0% 134 38.0% 0.015
>50 65 32.3% 35 17.4% 40 19.9% 61 30.3%
Nationality Sudanese 153 35.0% 56 12.8% 73 16.7% 155 35.5% 0.924
Eritrean 42 36.2% 14 12.1% 20 17.2% 40 34.5%
Histologic type aIDCNST 159 33.3% 65 13.6% 85 17.8% 168 35.2% 0.056
bILC 16 61.5% 1 3.8% 5 19.2% 4 15.4%
Medullary 0 0.0% 0 0.0% 0 0.0% 13 100.0%
Mucinous 16 94.1% 1 5.9% 0 0.0% 0 0.0%
Papillary 1 6.7% 3 20.0% 2 13.3% 9 60.0%
Cribriform 4 100.0% 0 0.0% 0 0.0% 0 0.0%
Pathologic tumour size pT1 45 47.9% 14 14.9% 10 10.6% 25 26.6% .041
pT2 74 31.1% 35 14.7% 48 20.2% 81 34.0%
pT3 43 31.2% 13 9.4% 23 16.7% 59 42.8%
pT4 27 40.3% 7 10.4% 9 13.4% 24 35.8%
Lymph Node involvement pN0 102 42.7% 31 13.0% 34 14.2% 72 30.1% 0.58
pN1 22 27.5% 10 12.5% 19 23.8% 29 36.3%
pN2 25 29.8% 15 17.9% 14 16.7% 30 35.7%
pN3 12 21.4% 8 14.3% 7 12.5% 29 51.8%
Nottingham Grade GI 19 67.9% 3 10.7% 4 14.3% 2 7.1% 0.000
GII 123 45.7% 25 9.3% 36 13.4% 85 31.6%
GIII 54 21.0% 42 16.3% 53 20.6% 108 42.0%
  1. a IDCNST= invasive ductal carcinoma, no special type, b ILC= invasive lobular carcinoma